{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["12"],"submitter":["Stueckelschweiger L"],"pubmed_abstract":["<b>Background and Purpose:</b> Acute ischemic stroke of the anterior circulation due to large vessel occlusion (LVO) is a multifactorial process, which causes neurologic symptoms of different degree. Our aim was to examine the impact of neuromorphologic and vascular correlates as well as clinical factors on acute symptom severity in LVO stroke. <b>Methods:</b> We selected LVO stroke patients with known onset time from a consecutive cohort which underwent multiparametric CT including non-contrast CT, CT angiography and CT perfusion (CTP) before thrombectomy. Software-based quantification was used to calculate CTP total ischemic and ischemic core volume. Symptom severity was assessed using the National Institutes of Health Stroke Scale (NIHSS) upon admission. Multivariable regression analysi"],"journal":["Frontiers in neurology"],"pagination":["651387"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7991695"],"repository":["biostudies-literature"],"pubmed_title":["Decomposing Acute Symptom Severity in Large Vessel Occlusion Stroke: Association With Multiparametric CT Imaging and Clinical Parameters."],"pmcid":["PMC7991695"],"pubmed_authors":["Fabritius MP","Ricke J","Tiedt S","Stueckelschweiger L","Grosu S","Kellert L","Reidler P","Herzberg M","Mueller F","Rueckel J","Maurus S","Kunz WG","Liebig T","Dimitriadis K","Puhr-Westerheide D"],"additional_accession":[]},"is_claimable":false,"name":"Decomposing Acute Symptom Severity in Large Vessel Occlusion Stroke: Association With Multiparametric CT Imaging and Clinical Parameters.","description":"<b>Background and Purpose:</b> Acute ischemic stroke of the anterior circulation due to large vessel occlusion (LVO) is a multifactorial process, which causes neurologic symptoms of different degree. Our aim was to examine the impact of neuromorphologic and vascular correlates as well as clinical factors on acute symptom severity in LVO stroke. <b>Methods:</b> We selected LVO stroke patients with known onset time from a consecutive cohort which underwent multiparametric CT including non-contrast CT, CT angiography and CT perfusion (CTP) before thrombectomy. Software-based quantification was used to calculate CTP total ischemic and ischemic core volume. Symptom severity was assessed using the National Institutes of Health Stroke Scale (NIHSS) upon admission. Multivariable regression analysi","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021","modification":"2026-04-18T01:31:03.774Z","creation":"2022-02-09T12:52:49.481Z"},"accession":"S-EPMC7991695","cross_references":{"pubmed":["33776900"],"doi":["10.3389/fneur.2021.651387"]}}