{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Dave RV"],"funding":["Cancer Research UK","Medical Research Council","National Institute for Health Research (NIHR)"],"pagination":["1785-1794"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7993073"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["124(11)"],"pubmed_abstract":["<h4>Background</h4>The B-MaP-C study aimed to determine alterations to breast cancer (BC) management during the peak transmission period of the UK COVID-19 pandemic and the potential impact of these treatment decisions.<h4>Methods</h4>This was a national cohort study of patients with early BC undergoing multidisciplinary team (MDT)-guided treatment recommendations during the pandemic, designated 'standard' or 'COVID-altered', in the preoperative, operative and post-operative setting.<h4>Findings</h4>Of 3776 patients (from 64 UK units) in the study, 2246 (59%) had 'COVID-altered' management. 'Bridging' endocrine therapy was used (n = 951) where theatre capacity was reduced. There was increasing access to COVID-19 low-risk theatres during the study period (59%). In line with national guidanc"],"journal":["British journal of cancer"],"pubmed_title":["Breast cancer management pathways during the COVID-19 pandemic: outcomes from the UK 'Alert Level 4' phase of the B-MaP-C study."],"pmcid":["PMC7993073"],"funding_grant_id":["21133","MC_U137686858","CL-2017-11-002","ACF-2019-21-004","PB-PG-0214-33065","NIHR300024"],"pubmed_authors":["Egbeare D","Hague M","Rusby JE","Barry PA","Krupa J","Krupa K","Goh NM","McCulley S","James K","Williams C","Sutton R","James R","Rutherford CL","Mathen V","Williams KE","Ferguson D","Taylor A","Chrysafi A","Abbott N","Rattay T","Knowles H","Robb HD","Nasir N","Gandamihardja T","Forouhi P","Hargreaves A","Carmichael A","Jacklin R","Ainsworth R","Rayter Z","Young I","Fafemi O","Hawkins S","Youssef MMG","Mullan M","Urquhart G","Abdalla ER","Jain U","Karagiannidis G","Zechmeister K","Gathani T","Bezzaa S","Kattakayam A","Allum WH","Garreffa E","Hill ADK","Poonawala S","Taxiarchi VP","Potter S","Girgis M","Massey J","Somasundaram S","Douek M","Isgar B","Gvaramadze A","Cheung KL","Al-Mufti R","Tanhueco A","Rana DS","Athanasiou I","Kirkham JJ","Turner J","Cariati M","Cain H","Kirwan CC","Gowda M","Stallard S","Dodwell D","Roy P","Mirshekar-Syahkal B","Roche N","Adwani A","Pereira B","Coles CE","Peck J","Salvador R","Olsen S","Drew P","Salih A","Pogson C","Horne S","Quinn E","Kalra L","Lafi M","Liptay-Wagner P","Rasheed T","Sahu A","Rapisarda F","Bramley M","Matey P","Tansley A","Sarakbi WA","Mortimer C","Betambeau N","Stanilov N","B-MaP-C study collaborative","Verroiotou M","Kothari A","Wignarajah P","Phyu SH","Mehta D","Khan LR","Critchley A","Kirkpatrick K","Achuthan R","Gill J","Laban C","Charalampoudis P","Ansari A","Benson J","Hadjiminas D","Sharma A","Kantola V","Vidya R","Parmeshwar R","Chagla L","Hurley AR","Sarker M","Sotheran W","Mallidis E","Lai LM","Elahi MB","Hussien M","Chatterjee S","Kaushik M","Gui G","Sharma N","Zammit C","Taraki Z","McManus P","Prusty L","Barnes N","Najeeb 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K","Al-Zawi ASA","McEvoy K","Jafferbhoy S","Thiruchelvam P","Hogan B","Cook L","Vashisht R","Bichoo RA","Peerlink I","Henderson J","McIntosh SA","Byrne G","Cook J","Govindarajulu S","Copson E","Remoundos D","Thekkinkattil D","Courtney A","Hardy R","Davies E","Horgan K","Bunza R","Romics L","Amin K","Thorne A","MacLean G","Absar M","Kim B","Dent H","Sweetland HM","Harries S","Turton P","Mazari F","Akolekar D","Burrah R","Soulsby R","Fairhurst K","Thomas R","Kallaway C","Sasi W","Sircar T","Hogben K","Thomson S","Sousa E","Bonomi R","Ives C","Cartlidge CWJ","Mondani G","Knight A","Goyal A","Law R","Vinayagam R","Laurence N","Kenny F","Barkeji M","Agrawal A","Tabbakh R","Vatish J","Zeidan B","Patani N","Aitken J","Saha S","Wilson C","Cox K","Soumian S","Highton L","Barua E","Azmy I","Mitchell G","Oni G","McIntosh J","Lambert K","Daltrey I","Dave RV","Mullen R","Chopra S","Brown I","Leff DR","Gahir J","Gallegos N","Hamad A","Athwal R","Shin H","Mathers H","Goyal S","Segaran A","Marla S","de Silva TS","Heeney A","Barker S","English RE","O'Connell R","Wahedna Y","Exarchos G","Mikhael Y","Pain S","Al-Ishaq Z","Batt J","Harding-Mackean C","Khalifa E","Khout H","Macmillan R","Imran A","Cuffolo G","Krzyzanowska C","Rathinaezhil R","McGoldrick C","Eid R","Harvey J","Masannat Y","Salman R","Elkorety M","Podesta C","Salman M","Fatayer H","Salem F","Suleiman U","Kiernan T","Betal D","Chambers A","Asgeirsson K","Courtney CA","Gopalan V","Jibril J","Nair R","Valassiadou K","Dumitru D","Power C","Shere M","Touqan N","King P","Agabiti E","Banerjee D","Maalo J","Navin C","Sibbering DM","Ravichandran D","Noor L","Pakzad F","Lund J","Joshi S","Ramzi S","Sloan SA","Sardar MV","Clayton E","Tillett R","Narayanan S","Seward J","Clayton G","Devalia H","Chouhan A","Tuffaha H","Simonca C","Horsnell JD","Fuller M","Coombs N","Smith S","Dua S","Pilgrm S","St John ERC"],"additional_accession":[]},"is_claimable":false,"name":"Breast cancer management pathways during the COVID-19 pandemic: outcomes from the UK 'Alert Level 4' phase of the B-MaP-C study.","description":"<h4>Background</h4>The B-MaP-C study aimed to determine alterations to breast cancer (BC) management during the peak transmission period of the UK COVID-19 pandemic and the potential impact of these treatment decisions.<h4>Methods</h4>This was a national cohort study of patients with early BC undergoing multidisciplinary team (MDT)-guided treatment recommendations during the pandemic, designated 'standard' or 'COVID-altered', in the preoperative, operative and post-operative setting.<h4>Findings</h4>Of 3776 patients (from 64 UK units) in the study, 2246 (59%) had 'COVID-altered' management. 'Bridging' endocrine therapy was used (n = 951) where theatre capacity was reduced. There was increasing access to COVID-19 low-risk theatres during the study period (59%). In line with national guidanc","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 May","modification":"2025-04-21T19:37:23.918Z","creation":"2022-02-11T01:28:41.65Z"},"accession":"S-EPMC7993073","cross_references":{"pubmed":["33767422"],"doi":["10.1038/s41416-020-01234-4"]}}