{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zappaterra M"],"funding":["Ministero dell'Istruzione, dell'Università e della Ricerca","Ministero dell’Istruzione, dell’Università e della Ricerca"],"pagination":["628"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC7997476"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(3)"],"pubmed_abstract":["To date, high-throughput technology such as RNA-sequencing has been successfully applied in livestock sciences to investigate molecular networks involved in complex traits, such as meat quality. Pork quality depends on several organoleptic, technological, and nutritional characteristics, and it is also influenced by the fatty acid (FA) composition of intramuscular fat (IMF). To explore the molecular networks associated with different IMF FA compositions, the <i>Semimembranosus</i> muscle (SM) from two groups of Italian Large White (ILW) heavy pigs divergent for SM IMF content was investigated using transcriptome analysis. After alignment and normalization, the obtained gene counts were used to perform the Weighted Correlation Network Analysis (WGCNA package in R environment). Palmitic and "],"journal":["Animals : an open access journal from MDPI"],"pubmed_title":["Dissecting the Gene Expression Networks Associated with Variations in the Major Components of the Fatty Acid <i>Semimembranosus</i> Muscle Profile in Large White Heavy Pigs."],"pmcid":["PMC7997476"],"funding_grant_id":["PRIN2015. No. 201549TZXB001"],"pubmed_authors":["Davoli R","Zappaterra M","Chillemi G","Gioiosa S","Zambonelli P"],"additional_accession":[]},"is_claimable":false,"name":"Dissecting the Gene Expression Networks Associated with Variations in the Major Components of the Fatty Acid <i>Semimembranosus</i> Muscle Profile in Large White Heavy Pigs.","description":"To date, high-throughput technology such as RNA-sequencing has been successfully applied in livestock sciences to investigate molecular networks involved in complex traits, such as meat quality. Pork quality depends on several organoleptic, technological, and nutritional characteristics, and it is also influenced by the fatty acid (FA) composition of intramuscular fat (IMF). To explore the molecular networks associated with different IMF FA compositions, the <i>Semimembranosus</i> muscle (SM) from two groups of Italian Large White (ILW) heavy pigs divergent for SM IMF content was investigated using transcriptome analysis. After alignment and normalization, the obtained gene counts were used to perform the Weighted Correlation Network Analysis (WGCNA package in R environment). Palmitic and ","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Feb","modification":"2026-04-07T15:06:45.76Z","creation":"2022-02-09T14:49:40.096Z"},"accession":"S-EPMC7997476","cross_references":{"pubmed":["33673460"],"doi":["10.3390/ani11030628"]}}