{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["70(1)"],"submitter":["Rahim MA"],"pubmed_abstract":["<i>Staphylococcus aureus</i> is currently a significant multidrug-resistant bacterium, causing severe healthcare-associated and community-acquired infections worldwide. The current antibiotic regimen against this pathogen is becoming ineffective due to resistance, in addition, they disrupt the normal microbiota. It highlights the urgent need for a pathogen-specific drug with high antibacterial efficacy against <i>S. aureus</i>. α-Viniferin, a bioactive phytochemical compound, has been reported to have excellent anti-<i>Staphylococcus</i> efficacy as a topical agent. However, so far, there were no clinical trials that have been conducted to elucidate its efficacy. The present study aimed to investigate the antibacterial efficacy of α-viniferin against <i>S. aureus</i> in a ten-day clinical "],"journal":["Polish journal of microbiology"],"pagination":["117-130"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8008767"],"repository":["biostudies-literature"],"pubmed_title":["A Clinical Trial to Evaluate the Efficacy of α-Viniferin in <i>Staphylococcus aureus</i> - Specific Decolonization without Depleting the Normal Microbiota of Nares."],"pmcid":["PMC8008767"],"pubmed_authors":["Kim S","Song HY","Lee S","Seo H","Jeong YK","Rahim MA","Tajdozian H","Kim M"],"additional_accession":[]},"is_claimable":false,"name":"A Clinical Trial to Evaluate the Efficacy of α-Viniferin in <i>Staphylococcus aureus</i> - Specific Decolonization without Depleting the Normal Microbiota of Nares.","description":"<i>Staphylococcus aureus</i> is currently a significant multidrug-resistant bacterium, causing severe healthcare-associated and community-acquired infections worldwide. The current antibiotic regimen against this pathogen is becoming ineffective due to resistance, in addition, they disrupt the normal microbiota. It highlights the urgent need for a pathogen-specific drug with high antibacterial efficacy against <i>S. aureus</i>. α-Viniferin, a bioactive phytochemical compound, has been reported to have excellent anti-<i>Staphylococcus</i> efficacy as a topical agent. However, so far, there were no clinical trials that have been conducted to elucidate its efficacy. The present study aimed to investigate the antibacterial efficacy of α-viniferin against <i>S. aureus</i> in a ten-day clinical ","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Mar","modification":"2025-04-18T16:51:45.589Z","creation":"2022-02-11T04:05:42.775Z"},"accession":"S-EPMC8008767","cross_references":{"pubmed":["33815533"],"doi":["10.33073/pjm-2021-011"]}}