biostudies-literatureUnknown8(3)Al-Shorafat DM<h4>Background</h4>Although the β-blocker propranolol is considered one of the most effective tremor treatments and other β-blockers are often prescribed to patients with tremor, those with partial β-agonist activity on β-adrenoreceptors can theoretically induce or exacerbate tremor. Here we report 2 patients with tremor induced or worsened by such β-blockers.<h4>Cases</h4>Case 1 is a 38-year-old man with worsening of tremor in both upper extremities after the introduction of pindolol as an adjunct treatment for severe depression. The tremor improved 1 month after discontinuing this medication. Case 2 is a 77-year-old woman with new bilateral hand tremor after receiving labetalol for the management of hypertension during a hospital admission. Tremor markedly attenuated after eliminating laMovement disorders clinical practice449-452https://www.ebi.ac.uk/biostudies/studies/S-EPMC8015902biostudies-literatureβ-Blocker-Induced Tremor.PMC8015902Al-Shorafat DMEspay AJFasano ABhowmick Sfalseβ-Blocker-Induced Tremor.<h4>Background</h4>Although the β-blocker propranolol is considered one of the most effective tremor treatments and other β-blockers are often prescribed to patients with tremor, those with partial β-agonist activity on β-adrenoreceptors can theoretically induce or exacerbate tremor. Here we report 2 patients with tremor induced or worsened by such β-blockers.<h4>Cases</h4>Case 1 is a 38-year-old man with worsening of tremor in both upper extremities after the introduction of pindolol as an adjunct treatment for severe depression. The tremor improved 1 month after discontinuing this medication. Case 2 is a 77-year-old woman with new bilateral hand tremor after receiving labetalol for the management of hypertension during a hospital admission. Tremor markedly attenuated after eliminating la2021-01-01T00:00:00Z2021 Apr2025-04-04T10:17:02.663Z2025-04-04T10:17:02.663ZS-EPMC80159023381667610.1002/mdc3.13176