{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Konig C"],"funding":["Deutsche Forschungsgemeinschaft","Biotechnology and Biological Sciences Research Council"],"pagination":["641472"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8017271"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11"],"pubmed_abstract":["The human protozoan parasite <i>Entamoeba histolytica</i> can live in the human intestine for months or years without generating any symptoms in the host. For unknown reasons, amoebae can suddenly destroy the intestinal mucosa and become invasive. This can lead to amoebic colitis or extraintestinal amoebiasis whereby the amoebae spread to other organs <i>via</i> the blood vessels, most commonly the liver where abscesses develop. <i>Entamoeba nuttalli</i> is the closest genetic relative of <i>E. histolytica</i> and is found in wild macaques. Another close relative is <i>E. dispar</i>, which asyptomatically infects the human intestine. Although all three species are closely related, only <i>E. histolytica</i> and <i>E. nuttalli</i> are able to penetrate their host's intestinal epithelium. Li"],"journal":["Frontiers in cellular and infection microbiology"],"pubmed_title":["Taxon-Specific Proteins of the Pathogenic <i>Entamoeba</i> Species <i>E. histolytica</i> and <i>E. nuttalli</i>."],"pmcid":["PMC8017271"],"funding_grant_id":["BBS/E/T/000PR9818"],"pubmed_authors":["Hall N","Roeder T","Metwally NG","Konig C","Honecker B","Bruchhaus I","Wilson IW","Weedall GD"],"additional_accession":[]},"is_claimable":false,"name":"Taxon-Specific Proteins of the Pathogenic <i>Entamoeba</i> Species <i>E. histolytica</i> and <i>E. nuttalli</i>.","description":"The human protozoan parasite <i>Entamoeba histolytica</i> can live in the human intestine for months or years without generating any symptoms in the host. For unknown reasons, amoebae can suddenly destroy the intestinal mucosa and become invasive. This can lead to amoebic colitis or extraintestinal amoebiasis whereby the amoebae spread to other organs <i>via</i> the blood vessels, most commonly the liver where abscesses develop. <i>Entamoeba nuttalli</i> is the closest genetic relative of <i>E. histolytica</i> and is found in wild macaques. Another close relative is <i>E. dispar</i>, which asyptomatically infects the human intestine. Although all three species are closely related, only <i>E. histolytica</i> and <i>E. nuttalli</i> are able to penetrate their host's intestinal epithelium. Li","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021","modification":"2026-04-07T21:51:22.962Z","creation":"2022-02-09T12:39:59.024Z"},"accession":"S-EPMC8017271","cross_references":{"pubmed":["33816346"],"doi":["10.3389/fcimb.2021.641472"]}}