{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhou X"],"funding":["the Beijing Municipal Science &amp; Technology commission national key research and development plan matching project"],"pagination":["599-605"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8018348"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["43(1)"],"pubmed_abstract":["The serum intact parathyroid hormone (iPTH) is associated with the prognosis of hemodialysis (HD) patients, however, its optimal range for reducing mortality remains inconsistent. We designed a prospective cohort study of 346 incident HD patients to assess the association between different serum iPTH level and mortality. According to the Kidney Disease Outcomes Quality Initiative (K/DOQI) international guidelines (2003), we divided patients into three groups (iPTH < 150 pg/mL, 150-300 pg/mL and >300 pg/mL). During the median follow-up of 58 months, 157 patients (45.38%) died. Multivariate Cox regression analysis showed that iPTH < 150 pg/mL and >300 pg/mL were associated with all-cause and cardiovascular mortality. Then, we performed a sensitivity analysis of patients divided into 6 serum "],"journal":["Renal failure"],"pubmed_title":["The optimal range of serum intact parathyroid hormone for a lower risk of mortality in the incident hemodialysis patients."],"pmcid":["PMC8018348"],"funding_grant_id":["Z161100002616005"],"pubmed_authors":["Guo Y","Luo Y","Zhou X"],"additional_accession":[]},"is_claimable":false,"name":"The optimal range of serum intact parathyroid hormone for a lower risk of mortality in the incident hemodialysis patients.","description":"The serum intact parathyroid hormone (iPTH) is associated with the prognosis of hemodialysis (HD) patients, however, its optimal range for reducing mortality remains inconsistent. We designed a prospective cohort study of 346 incident HD patients to assess the association between different serum iPTH level and mortality. According to the Kidney Disease Outcomes Quality Initiative (K/DOQI) international guidelines (2003), we divided patients into three groups (iPTH < 150 pg/mL, 150-300 pg/mL and >300 pg/mL). During the median follow-up of 58 months, 157 patients (45.38%) died. Multivariate Cox regression analysis showed that iPTH < 150 pg/mL and >300 pg/mL were associated with all-cause and cardiovascular mortality. Then, we performed a sensitivity analysis of patients divided into 6 serum ","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Dec","modification":"2025-04-04T12:34:07.686Z","creation":"2025-04-04T12:34:07.686Z"},"accession":"S-EPMC8018348","cross_references":{"pubmed":["33781171"],"doi":["10.1080/0886022X.2021.1903927"]}}