biostudies-literatureQuinones ARNIA NIH HHS402-409https://www.ebi.ac.uk/biostudies/studies/S-EPMC8024615biostudies-literatureUnknown59(5)<h4>Background</h4>Our understanding of how multimorbidity progresses and changes is nascent.<h4>Objectives</h4>Assess multimorbidity changes among racially/ethnically diverse middle-aged and older adults.<h4>Design, setting, and participants</h4>Prospective cohort study using latent class analysis to identify multimorbidity combinations over 16 years, and multinomial logistic models to assess change relative to baseline class membership. Health and Retirement Study respondents (age 51 y and above) in 1998 and followed through 2014 (N=17,297).<h4>Measures</h4>Multimorbidity latent classes of: hypertension, heart disease, lung disease, diabetes, cancer, arthritis, stroke, high depressive symptoms.<h4>Results</h4>Three latent classes were identified in 1998: minimal disease (45.8% of particiMedical careRacial and Ethnic Differences in Multimorbidity Changes Over Time.PMC8024615P30 AG021342R01 AG055681R01 AG047891Allore HGNagel CLBotoseneanu AQuinones ARNewsom JTMarkwardt SElman MRDorr DAfalseRacial and Ethnic Differences in Multimorbidity Changes Over Time.<h4>Background</h4>Our understanding of how multimorbidity progresses and changes is nascent.<h4>Objectives</h4>Assess multimorbidity changes among racially/ethnically diverse middle-aged and older adults.<h4>Design, setting, and participants</h4>Prospective cohort study using latent class analysis to identify multimorbidity combinations over 16 years, and multinomial logistic models to assess change relative to baseline class membership. Health and Retirement Study respondents (age 51 y and above) in 1998 and followed through 2014 (N=17,297).<h4>Measures</h4>Multimorbidity latent classes of: hypertension, heart disease, lung disease, diabetes, cancer, arthritis, stroke, high depressive symptoms.<h4>Results</h4>Three latent classes were identified in 1998: minimal disease (45.8% of partici2021-01-01T00:00:00Z2021 May2025-04-04T10:16:54.512Z2025-04-04T10:16:54.512ZS-EPMC80246153382182910.1097/mlr.000000000000152710.1097/MLR.0000000000001527