biostudies-literaturePatterson Gentile CNEI NIH HHS1https://www.ebi.ac.uk/biostudies/studies/S-EPMC8024780biostudies-literatureUnknown10(4)<h4>Purpose</h4>Peak amplitude and peak latency in the pattern reversal visual evoked potential (prVEP) vary with maturation. We considered that principal component analysis (PCA) may be used to describe age-related variation over the entire prVEP time course and provide a means of modeling and removing variation due to developmental age.<h4>Methods</h4>PrVEP was recorded from 155 healthy subjects ages 11 to 19 years at two time points. We created a model of the prVEP by identifying principal components (PCs) that explained >95% of the variance in a "training" dataset of 40 subjects. We examined the ability of the PCs to explain variance in an age- and sex-matched "validation" dataset (n = 40) and calculated the intrasubject reliability of the PC coefficients between the two time points. WTranslational vision science & technologyDevelopmental Effects on Pattern Visual Evoked Potentials Characterized by Principal Component Analysis.PMC8024780P30 EY001583Arbogast KBMaster CJoshi NRCiuffreda KJAguirre GKPatterson Gentile CfalseDevelopmental Effects on Pattern Visual Evoked Potentials Characterized by Principal Component Analysis.<h4>Purpose</h4>Peak amplitude and peak latency in the pattern reversal visual evoked potential (prVEP) vary with maturation. We considered that principal component analysis (PCA) may be used to describe age-related variation over the entire prVEP time course and provide a means of modeling and removing variation due to developmental age.<h4>Methods</h4>PrVEP was recorded from 155 healthy subjects ages 11 to 19 years at two time points. We created a model of the prVEP by identifying principal components (PCs) that explained >95% of the variance in a "training" dataset of 40 subjects. We examined the ability of the PCs to explain variance in an age- and sex-matched "validation" dataset (n = 40) and calculated the intrasubject reliability of the PC coefficients between the two time points. W2021-01-01T00:00:00Z2021 Apr2025-04-26T08:20:41.778Z2025-04-06T12:38:03.674ZS-EPMC80247803400398010.1167/tvst.10.4.1