biostudies-literatureClemens JQNIDA NIH HHSNational Institute of Diabetes and Digestive and Kidney DiseasesNIDDK NIH HHS1803-1814https://www.ebi.ac.uk/biostudies/studies/S-EPMC8025696biostudies-literatureUnknown39(6)<h4>Aims</h4>The Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network initiated a second observational cohort study-the Symptom Patterns Study (SPS)-to further investigate the underlying pathophysiology of Urologic Chronic Pelvic Pain Syndrome (UCPPS) and to discover factors associated with longitudinal symptom changes and responses to treatments.<h4>Methods</h4>This multisite cohort study of males and females with UCPPS features a run-in period of four weekly web-based symptom assessments before a baseline visit, followed by quarterly assessments up to 36 months. Controls were also recruited and assessed at baseline and 6 months. Extensive clinical data assessing urological symptoms, nonurological pain, chronic overlapping pain syndromes, and psychosocialNeurourology and urodynamicsThe Multidisciplinary Approach to The Study of Chronic Pelvic Pain (MAPP) Research Network*: Design and implementation of the Symptom Patterns Study (SPS).PMC8025696U01 DK082370U24 DK082333U01 DK103227U24 DK082316U01 DK082344U01 DK082333U01 DK082345U01 DK082342U01 DK082315U01 DK082316U01 DK082325U01 DK103260U01 DK103271K24 DA029262Harte SELucia MSLandis JRMoldwin RMRodriguez LVKlumpp DJMullins CNaliboff BDSchaeffer AJClauw DJPontari MAWilliams DAAndriole GLBuchwald DStephens-Shields AJKutch JJMackey SSchrepf ADLai HHKreder KJvan Bokhoven AMayer EAClemens JQfalseThe Multidisciplinary Approach to The Study of Chronic Pelvic Pain (MAPP) Research Network*: Design and implementation of the Symptom Patterns Study (SPS).<h4>Aims</h4>The Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network initiated a second observational cohort study-the Symptom Patterns Study (SPS)-to further investigate the underlying pathophysiology of Urologic Chronic Pelvic Pain Syndrome (UCPPS) and to discover factors associated with longitudinal symptom changes and responses to treatments.<h4>Methods</h4>This multisite cohort study of males and females with UCPPS features a run-in period of four weekly web-based symptom assessments before a baseline visit, followed by quarterly assessments up to 36 months. Controls were also recruited and assessed at baseline and 6 months. Extensive clinical data assessing urological symptoms, nonurological pain, chronic overlapping pain syndromes, and psychosocial2020-01-01T00:00:00Z2020 Aug2025-04-04T11:00:58.947Z2022-02-11T00:52:59.453ZS-EPMC80256963257825710.1002/nau.24423