{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kamimura D"],"funding":["Jackson State University","NIDDK NIH HHS","National Institute of Diabetes and Digestive and Kidney Diseases","NHLBI NIH HHS","NIMHD NIH HHS","National Institute of General Medical Sciences","NIGMS NIH HHS"],"pagination":["901-911"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8026689"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["96(4)"],"pubmed_abstract":["<h4>Objective</h4>To examine associations between physical activity (PA), inflammation, coronary artery calcification (CAC), and incident coronary heart disease (CHD) in African Americans.<h4>Methods</h4>Among Jackson Heart Study participants without prevalent CHD at baseline (n=4295), we examined the relationships between PA and high-sensitivity C-reactive protein, the presence of CAC (Agatston score ≥100), and incident CHD. Based on the American Heart Association's Life's Simple 7 metrics, participants were classified as having poor, intermediate, or ideal PA.<h4>Results</h4>After adjustment for possible confounding factors, ideal PA was associated with lower high-sensitivity C-reactive protein levels (β, -0.15; 95% CI, -0.15 to -0.002) and a lower prevalence of CAC (odds ratio, 0.70; 95"],"journal":["Mayo Clinic proceedings"],"pubmed_title":["Physical Activity, Inflammation, Coronary Artery Calcification, and Incident Coronary Heart Disease in African Americans: Insights From the Jackson Heart Study."],"pmcid":["PMC8026689"],"funding_grant_id":["HHSN268201800015I","HHSN268201800012C","HHSN268201800011C","P20 GM104357","HHSN268201800013I","U54 GM104940","K08 DK099415","HHSN268201800014C","U54 GM115428"],"pubmed_authors":["Suzuki T","Guild CS","Loprinzi PD","Oshunbade AA","Hall JE","Correa A","Kamimura D","Clark D","Cain-Shields LR","Ashley KE","Hall ME","Blaha MJ","Butler J","Newton R"],"additional_accession":[]},"is_claimable":false,"name":"Physical Activity, Inflammation, Coronary Artery Calcification, and Incident Coronary Heart Disease in African Americans: Insights From the Jackson Heart Study.","description":"<h4>Objective</h4>To examine associations between physical activity (PA), inflammation, coronary artery calcification (CAC), and incident coronary heart disease (CHD) in African Americans.<h4>Methods</h4>Among Jackson Heart Study participants without prevalent CHD at baseline (n=4295), we examined the relationships between PA and high-sensitivity C-reactive protein, the presence of CAC (Agatston score ≥100), and incident CHD. Based on the American Heart Association's Life's Simple 7 metrics, participants were classified as having poor, intermediate, or ideal PA.<h4>Results</h4>After adjustment for possible confounding factors, ideal PA was associated with lower high-sensitivity C-reactive protein levels (β, -0.15; 95% CI, -0.15 to -0.002) and a lower prevalence of CAC (odds ratio, 0.70; 95","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Apr","modification":"2025-04-29T11:30:41.939Z","creation":"2025-04-06T19:55:11.496Z"},"accession":"S-EPMC8026689","cross_references":{"pubmed":["33714604"],"doi":["10.1016/j.mayocp.2020.09.042"]}}