biostudies-literatureSpencer RNCATS NIH HHSNIH National Center for Advancing Translational Sciences525-532https://www.ebi.ac.uk/biostudies/studies/S-EPMC8034777biostudies-literatureUnknown30(4)<h4>Background</h4>Recurrent gynecologic cancer patients experience symptoms that affect psychologic, emotional, social, and physical well-being. Chemotherapy can further exacerbate these symptoms. Poor mood, pain, and fatigue are linked and are detrimental to quality of life. Interventions targeting these symptoms may improve patient-reported outcomes and performance status.<h4>Objectives</h4>To determine the ability of a humorous digital media attention diversion to improve symptom domains of positive and negative mood during chemotherapy for patients with recurrent gynecologic cancers.<h4>Study design</h4>This randomized, crossover clinical trial enrolled women with recurrent gynecologic cancers. Subjects participated over three cycles of chemotherapy. The primary outcome was the changeInternational journal of gynecological cancer : official journal of the International Gynecological Cancer SocietyA digital media attention diversion improves mood and fear in patients receiving chemotherapy for recurrent gynecologic malignancies: results of a randomized trial.PMC8034777UL1 TR002373UL1TR002373Alexander VCostanzo EMarx NSpencer RWoo KEickhoff JRose SfalseA digital media attention diversion improves mood and fear in patients receiving chemotherapy for recurrent gynecologic malignancies: results of a randomized trial.<h4>Background</h4>Recurrent gynecologic cancer patients experience symptoms that affect psychologic, emotional, social, and physical well-being. Chemotherapy can further exacerbate these symptoms. Poor mood, pain, and fatigue are linked and are detrimental to quality of life. Interventions targeting these symptoms may improve patient-reported outcomes and performance status.<h4>Objectives</h4>To determine the ability of a humorous digital media attention diversion to improve symptom domains of positive and negative mood during chemotherapy for patients with recurrent gynecologic cancers.<h4>Study design</h4>This randomized, crossover clinical trial enrolled women with recurrent gynecologic cancers. Subjects participated over three cycles of chemotherapy. The primary outcome was the change2020-01-01T00:00:00Z2020 Apr2025-05-29T18:59:08.329Z2022-02-09T15:54:13.279ZS-EPMC80347773212295110.1136/ijgc-2019-001185