{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Milstone AM"],"funding":["AHRQ HHS"],"pagination":["431-439"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8039053"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["42(4)"],"pubmed_abstract":["<h4>Objective</h4>To evaluate the effect of 70% isopropyl alcohol-impregnated central venous catheter caps on ambulatory central-line-associated bloodstream infections (CLABSIs) in pediatric hematology-oncology patients.<h4>Design</h4>This study was a 24-month, cluster-randomized, 2 period, crossover clinical trial.<h4>Setting</h4>The study was conducted in 15 pediatric healthcare institutions, including 16 pediatric hematology-oncology clinics.<h4>Participants</h4>All patients with an external central line followed at 1 of the 16 hematology-oncology clinics.<h4>Intervention</h4>Usual ambulatory central-line care per each institution using 70% isopropyl alcohol-impregnated caps at home compared to usual ambulatory central-line care in each institution without using 70% isopropyl alcohol-im"],"journal":["Infection control and hospital epidemiology"],"pubmed_title":["Alcohol-impregnated caps and ambulatory central-line-associated bloodstream infections (CLABSIs): A randomized clinical trial."],"pmcid":["PMC8039053"],"funding_grant_id":["R01 HS022870"],"pubmed_authors":["Rosenberg C","Yenokyan G","Koontz DW","Miller MR","CCLIP Authorship Group","Milstone AM"],"additional_accession":[]},"is_claimable":false,"name":"Alcohol-impregnated caps and ambulatory central-line-associated bloodstream infections (CLABSIs): A randomized clinical trial.","description":"<h4>Objective</h4>To evaluate the effect of 70% isopropyl alcohol-impregnated central venous catheter caps on ambulatory central-line-associated bloodstream infections (CLABSIs) in pediatric hematology-oncology patients.<h4>Design</h4>This study was a 24-month, cluster-randomized, 2 period, crossover clinical trial.<h4>Setting</h4>The study was conducted in 15 pediatric healthcare institutions, including 16 pediatric hematology-oncology clinics.<h4>Participants</h4>All patients with an external central line followed at 1 of the 16 hematology-oncology clinics.<h4>Intervention</h4>Usual ambulatory central-line care per each institution using 70% isopropyl alcohol-impregnated caps at home compared to usual ambulatory central-line care in each institution without using 70% isopropyl alcohol-im","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Apr","modification":"2026-05-02T22:39:43.386Z","creation":"2025-04-07T07:25:35.093Z"},"accession":"S-EPMC8039053","cross_references":{"pubmed":["33040755"],"doi":["10.1017/ice.2020.467"]}}