{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["9(6)"],"submitter":["Yi C"],"pubmed_abstract":["<h4>Background</h4>Currently, the tumor, node, and metastasis (TNM) staging system has a limited value in prognostic stratification for neuroendocrine tumors of the lung (NETL). A specific pathological staging system was therefore explored.<h4>Methods</h4>Two cohorts were assessed: the training cohort was composed of surgically treated patients from the Surveillance, Epidemiologic, and End Results (SEER) database [2004-2015]; the Shanghai cohort included Shanghai resident patients treated at Shanghai Pulmonary Hospital [2009-2018]. Multivariable Cox regression analysis was performed to identify factors associated with overall survival. A new staging system was proposed based on survival tree, and was further compared with the 8<sup>th</sup> edition of the TNM staging system.<h4>Results</h4"],"journal":["Annals of translational medicine"],"pagination":["447"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8039668"],"repository":["biostudies-literature"],"pubmed_title":["Improvement of pathological staging system for neuroendocrine tumors of the lung."],"pmcid":["PMC8039668"],"pubmed_authors":["Song N","Zhu Y","Jiang G","Zhang H","Wu C","Yi C","Zhang L","Dai J","Zhang P"],"additional_accession":[]},"is_claimable":false,"name":"Improvement of pathological staging system for neuroendocrine tumors of the lung.","description":"<h4>Background</h4>Currently, the tumor, node, and metastasis (TNM) staging system has a limited value in prognostic stratification for neuroendocrine tumors of the lung (NETL). A specific pathological staging system was therefore explored.<h4>Methods</h4>Two cohorts were assessed: the training cohort was composed of surgically treated patients from the Surveillance, Epidemiologic, and End Results (SEER) database [2004-2015]; the Shanghai cohort included Shanghai resident patients treated at Shanghai Pulmonary Hospital [2009-2018]. Multivariable Cox regression analysis was performed to identify factors associated with overall survival. A new staging system was proposed based on survival tree, and was further compared with the 8<sup>th</sup> edition of the TNM staging system.<h4>Results</h4","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Mar","modification":"2025-04-04T21:24:34.784Z","creation":"2025-04-04T21:24:34.784Z"},"accession":"S-EPMC8039668","cross_references":{"pubmed":["33850844"],"doi":["10.21037/atm-20-5910"]}}