{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Zhang G"],"funding":["Innovation of Science and Technology Project, Nanjing Military Region"],"pagination":["249"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8042966"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["16(1)"],"pubmed_abstract":["<h4>Introduction</h4>The experiment was undertaken to estimate the effect of BMSC seeding in different scaffold incorporation with HBO on the repair of a seawater-immersed bone defect. And future compared n-HA/PLGA with β-TCP/PLGA as a scaffold in treatment effect of the seawater-immersed bone defect.<h4>Methods</h4>Sixty New Zealand White rabbits with standard seawater defect in radius were randomly divided into group A (implant with nothing), group B (implanted with autogenous bone), group C (implanted with n-HA/PLGA/BMSCs), and group D (implanted with β-TCP/PLGA/BMSCs). After the implant, each rabbit receives HBO treatment at 2.4 ATA 100% oxygen for 120 min/day for 2 weeks. Radiograph, histological, and biomechanical examinations were used to analyze osteogenesis.<h4>Result</h4>X-ray an"],"journal":["Journal of orthopaedic surgery and research"],"pubmed_title":["BMSC seeding in different scaffold incorporation with hyperbaric oxygen treats seawater-immersed bony defect."],"pmcid":["PMC8042966"],"funding_grant_id":["11Z011"],"pubmed_authors":["Zhang G","Chen X","Chen C","Cheng X","Ma W"],"additional_accession":[]},"is_claimable":false,"name":"BMSC seeding in different scaffold incorporation with hyperbaric oxygen treats seawater-immersed bony defect.","description":"<h4>Introduction</h4>The experiment was undertaken to estimate the effect of BMSC seeding in different scaffold incorporation with HBO on the repair of a seawater-immersed bone defect. And future compared n-HA/PLGA with β-TCP/PLGA as a scaffold in treatment effect of the seawater-immersed bone defect.<h4>Methods</h4>Sixty New Zealand White rabbits with standard seawater defect in radius were randomly divided into group A (implant with nothing), group B (implanted with autogenous bone), group C (implanted with n-HA/PLGA/BMSCs), and group D (implanted with β-TCP/PLGA/BMSCs). After the implant, each rabbit receives HBO treatment at 2.4 ATA 100% oxygen for 120 min/day for 2 weeks. Radiograph, histological, and biomechanical examinations were used to analyze osteogenesis.<h4>Result</h4>X-ray an","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Apr","modification":"2025-04-04T18:37:28.786Z","creation":"2022-02-09T15:08:16.201Z"},"accession":"S-EPMC8042966","cross_references":{"pubmed":["33849602"],"doi":["10.1186/s13018-021-02368-8"]}}