biostudies-literatureParrello BNational Institute of Allergy and Infectious DiseasesNIAID NIH HHSe0250092https://www.ebi.ac.uk/biostudies/studies/S-EPMC8049274biostudies-literatureUnknown16(4)Large amounts of metagenomically-derived data are submitted to PATRIC for analysis. In the future, we expect even more jobs submitted to PATRIC will use metagenomic data. One in-demand use case is the extraction of near-complete draft genomes from assembled contigs of metagenomic origin. The PATRIC metagenome binning service utilizes the PATRIC database to furnish a large, diverse set of reference genomes. We provide a new service for supervised extraction and annotation of high-quality, near-complete genomes from metagenomically-derived contigs. Reference genomes are assigned to putative draft genome bins based on the presence of single-copy universal marker roles in the sample, and contigs are sorted into these bins by their similarity to reference genomes in PATRIC. Each set of binned cPloS oneSupervised extraction of near-complete genomes from metagenomic samples: A new service in PATRIC.PMC8049274HHSN272201400027CButler RChlenski POverbeek RParrello BPusch GDfalseSupervised extraction of near-complete genomes from metagenomic samples: A new service in PATRIC.Large amounts of metagenomically-derived data are submitted to PATRIC for analysis. In the future, we expect even more jobs submitted to PATRIC will use metagenomic data. One in-demand use case is the extraction of near-complete draft genomes from assembled contigs of metagenomic origin. The PATRIC metagenome binning service utilizes the PATRIC database to furnish a large, diverse set of reference genomes. We provide a new service for supervised extraction and annotation of high-quality, near-complete genomes from metagenomically-derived contigs. Reference genomes are assigned to putative draft genome bins based on the presence of single-copy universal marker roles in the sample, and contigs are sorted into these bins by their similarity to reference genomes in PATRIC. Each set of binned c2021-01-01T00:00:00Z20212025-04-26T07:25:18.376Z2022-02-09T15:52:45.544ZS-EPMC80492743385722910.1371/journal.pone.0250092