biostudies-literatureUnknownKass MANEI NIH HHS<h4>Importance</h4>Ocular hypertension is an important risk factor for the development of primary open-angle glaucoma (POAG). Data from long-term follow-up can be used to inform the management of patients with ocular hypertension.<h4>Objective</h4>To determine the cumulative incidence and severity of POAG after 20 years of follow-up among participants in the Ocular Hypertension Treatment Study.<h4>Design, setting, and participants</h4>Participants in the Ocular Hypertension Treatment Study were followed up from February 1994 to December 2008 in 22 clinics. Data were collected after 20 years of follow-up (from January 2016 to April 2019) or within 2 years of death. Analyses were performed from July 2019 to December 2020.<h4>Interventions</h4>From February 28, 1994, to June 2, 2002 (phase 1)JAMA ophthalmologyhttps://www.ebi.ac.uk/biostudies/studies/S-EPMC8050785biostudies-literatureAssessment of Cumulative Incidence and Severity of Primary Open-Angle Glaucoma Among Participants in the Ocular Hypertension Treatment Study After 20 Years of Follow-up.PMC8050785UG1 EY025180UG1 EY025183UG1 EY025182UG1 EY025181Beck ADClark KPistorius SWilliams DDillon BPatorgis CJClark CJuzych MSOrengo-Nania SGrand-Drossner SCobb SHFabrizio MJSankar PSNiemczyk JLJampel HDKass MAShukairy ASultze JLSawchyn AKGiaconi JHall JBlumberg DMDe Moraes CGMorris PAGutowski MKinast RMDirkes KHigginbotham EJMohay-Ambrus JParrish RKBaik AKHeuer DJones EPHardney KSPlumb KSmith MAEverett DFO'Grady JMWeinreb RNVarner EAQuigley HABennett JRPatel DREsquiabro MYJohnson CAMiller RAtakulova MLiebmann JMHodapp ESoltau JBKalarn SCostarides APMoroi SHunsicker MVega SFischbach EPalmberg PVandenbroucke RWeiss HSHuecker JBMiller-Ellis EGBhorade AMQuinn MHaertter LWCioffi GAFantin ASchwartz ALYoung JWHeuer DKWood SKBennett LCKhanna CLPiltz-Seymour JRAshburn FSMansberger SLLaw SKWilson BSCrandall DAWells JOu YGordon MOArnold MSKeltner JLWashington CMilanovic CMSlight JRAdcock EMcManus PELeming LColeman ALBalasubramaniam SCLind JTImami NRDunn DALiu LPeterson CAWeber PAAl-Aswad LALong TSoltau JGedee SJZangwill LMBrandt JDBhattacharjee PVitelli CSavatovsky EVan Conett LAHughes BABennett GRSaeedi OJBottorff MLim MCGoldman CLeef DLeger ADarnley-Fisch DADuarte PBLamping KAFeuer WChang PTGilbert JLGutkowski MOcular Hypertension Study GroupProudfoot JMiller JPfalseAssessment of Cumulative Incidence and Severity of Primary Open-Angle Glaucoma Among Participants in the Ocular Hypertension Treatment Study After 20 Years of Follow-up.<h4>Importance</h4>Ocular hypertension is an important risk factor for the development of primary open-angle glaucoma (POAG). Data from long-term follow-up can be used to inform the management of patients with ocular hypertension.<h4>Objective</h4>To determine the cumulative incidence and severity of POAG after 20 years of follow-up among participants in the Ocular Hypertension Treatment Study.<h4>Design, setting, and participants</h4>Participants in the Ocular Hypertension Treatment Study were followed up from February 1994 to December 2008 in 22 clinics. Data were collected after 20 years of follow-up (from January 2016 to April 2019) or within 2 years of death. Analyses were performed from July 2019 to December 2020.<h4>Interventions</h4>From February 28, 1994, to June 2, 2002 (phase 1)2021-01-01T00:00:00Z2021 Apr2026-05-02T22:41:44.391Z2025-04-04T13:30:46.03ZS-EPMC80507853385643410.1001/jamaophthalmol.2021.0341