biostudies-literatureUnknown22(1)Khoo BZE<h4>Background</h4>Coronavirus Disease 2019 (COVID-19) infection has been associated with a hypercoagulable state with increased reports of thrombotic events. Acute kidney injury requiring dialysis is common in critically ill patients and circuit clotting compromises efficacy of treatment. This study aims to analyze the circuit life and circuit clotting during continuous kidney replacement therapy (CKRT) and intermittent hemodialysis in patients with and without COVID-19.<h4>Methods</h4>This is a single-center, retrospective cohort study in critically ill patients undergoing CKRT or intermittent hemodialysis between 1 February 2020 to 22 May 2020. Patients in the intensive care unit (ICU) with COVID-19 infection and contemporary controls who tested negative were included. Co-primary outcomBMC nephrology141https://www.ebi.ac.uk/biostudies/studies/S-EPMC8056790biostudies-literatureDialysis circuit clotting in critically ill patients with COVID-19 infection.PMC8056790Lim RSSee YPYeo SCKhoo BZEfalseDialysis circuit clotting in critically ill patients with COVID-19 infection.<h4>Background</h4>Coronavirus Disease 2019 (COVID-19) infection has been associated with a hypercoagulable state with increased reports of thrombotic events. Acute kidney injury requiring dialysis is common in critically ill patients and circuit clotting compromises efficacy of treatment. This study aims to analyze the circuit life and circuit clotting during continuous kidney replacement therapy (CKRT) and intermittent hemodialysis in patients with and without COVID-19.<h4>Methods</h4>This is a single-center, retrospective cohort study in critically ill patients undergoing CKRT or intermittent hemodialysis between 1 February 2020 to 22 May 2020. Patients in the intensive care unit (ICU) with COVID-19 infection and contemporary controls who tested negative were included. Co-primary outcom2021-01-01T00:00:00Z2021 Apr2025-04-21T19:29:35.413Z2022-02-09T15:54:22.681ZS-EPMC80567903387908610.1186/s12882-021-02357-3