biostudies-literatureAl-Khersan HNational Eye InstituteNEI NIH HHSResearch to Prevent Blindness292-300https://www.ebi.ac.uk/biostudies/studies/S-EPMC8058287biostudies-literatureUnknown224<h4>Purpose</h4>We compared the ability of ophthalmologists to identify neovascularization (NV) in patients with proliferative diabetic retinopathy using swept-source optical coherence tomography angiography (SS-OCTA) and fluorescein angiography (FA).<h4>Design</h4>Retrospective study comparing diagnostic instruments.<h4>Methods</h4>Eyes with proliferative diabetic retinopathy or severe nonproliferative diabetic retinopathy and a high suspicion of NV based on clinical examination were imaged using SS-OCTA and FA at the same visit. Two separate grading sets consisting of scrambled, anonymized SS-OCTA and FA images were created. The ground truth for presence of NV was established by consensus of 2 graders with OCTA experience who did not participate in the subsequent assessment of NV in thisAmerican journal of ophthalmologyComparison Between Graders in Detection of Diabetic Neovascularization With Swept Source Optical Coherence Tomography Angiography and Fluorescein Angiography.PMC8058287P30 EY014801Hussain RMRussell SRRosenfeld PJPatel NAHariprasad SMRussell JFHinkle JWHaddock LJLazzarini TAGregori GShi YWang LFowler BJScott NLFeuer WYannuzzi NASridhar JAl-Khersan HBarikian ASmiddy WEfalseComparison Between Graders in Detection of Diabetic Neovascularization With Swept Source Optical Coherence Tomography Angiography and Fluorescein Angiography.<h4>Purpose</h4>We compared the ability of ophthalmologists to identify neovascularization (NV) in patients with proliferative diabetic retinopathy using swept-source optical coherence tomography angiography (SS-OCTA) and fluorescein angiography (FA).<h4>Design</h4>Retrospective study comparing diagnostic instruments.<h4>Methods</h4>Eyes with proliferative diabetic retinopathy or severe nonproliferative diabetic retinopathy and a high suspicion of NV based on clinical examination were imaged using SS-OCTA and FA at the same visit. Two separate grading sets consisting of scrambled, anonymized SS-OCTA and FA images were created. The ground truth for presence of NV was established by consensus of 2 graders with OCTA experience who did not participate in the subsequent assessment of NV in this2021-01-01T00:00:00Z2021 Apr2025-04-29T11:30:00.734Z2025-04-06T19:55:08.365ZS-EPMC80582873330981210.1016/j.ajo.2020.11.020