{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["McNeece AJ"],"funding":["University of Chicago","Directorate for Mathematical and Physical Sciences","U.S. Department of Defense","Argonne National Laboratory","Alfred P. Sloan Foundation","National Institute of General Medical Sciences","NIGMS NIH HHS"],"pagination":["3869-3872"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8058320"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["57(32)"],"pubmed_abstract":["Biology employs exquisite control over proton, electron, H-atom, or H<sub>2</sub> transfer. Similar control in synthetic systems has the potential to facilitate efficient and selective catalysis. Here we report a dihydrazonopyrrole Ni complex where an H<sub>2</sub> equivalent can be stored on the ligand periphery without metal-based redox changes and can be leveraged for catalytic hydrogenations. Kinetic and computational analysis suggests ligand hydrogenation proceeds by H<sub>2</sub> association followed by H-H scission. This complex is an unusual example where a synthetic system can mimic biology's ability to mediate H<sub>2</sub> transfer via secondary coordination sphere-based processes."],"journal":["Chemical communications (Cambridge, England)"],"pubmed_title":["Catalytic hydrogenation enabled by ligand-based storage of hydrogen."],"pmcid":["PMC8058320"],"funding_grant_id":["DE-AC02-06CH11357","FG 2019 11497","00003765","CHE-1834750","R35 GM133470"],"pubmed_authors":["Jesse KA","Schneider JE","McNeece AJ","Filatov AS","Anderson JS"],"additional_accession":[]},"is_claimable":false,"name":"Catalytic hydrogenation enabled by ligand-based storage of hydrogen.","description":"Biology employs exquisite control over proton, electron, H-atom, or H<sub>2</sub> transfer. Similar control in synthetic systems has the potential to facilitate efficient and selective catalysis. Here we report a dihydrazonopyrrole Ni complex where an H<sub>2</sub> equivalent can be stored on the ligand periphery without metal-based redox changes and can be leveraged for catalytic hydrogenations. Kinetic and computational analysis suggests ligand hydrogenation proceeds by H<sub>2</sub> association followed by H-H scission. This complex is an unusual example where a synthetic system can mimic biology's ability to mediate H<sub>2</sub> transfer via secondary coordination sphere-based processes.","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Apr","modification":"2025-04-04T10:17:11.046Z","creation":"2025-04-04T10:17:11.046Z"},"accession":"S-EPMC8058320","cross_references":{"pubmed":["33729221"],"doi":["10.1039/d0cc08236h"]}}