{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["10(4)"],"submitter":["Nair A"],"pubmed_abstract":["Ehrlichia ruminantium, a tick-borne rickettsial, causes heartwater in ruminants resulting from vascular damage. Severity of heartwater varies greatly in ruminant species and breeds, age of animals and for diverse geographic E. ruminantium strains. E. ruminantium and a tick vector, Amblyomma variegatum, originating from Africa, are well established in certain Caribbean islands two centuries ago. Besides the possibility of introduction of heartwater through African exotic animal importation, presence of the pathogen, and the tick vector in the Caribbean pose a high risk to ruminants in the USA and other western hemisphere countries. Scientific evidence supporting the heartwater threat to nonendemic regions, however, is lacking. We describe the first infection study in sheep reared in the USA"],"journal":["Pathogens (Basel, Switzerland)"],"pagination":["451"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8070521"],"repository":["biostudies-literature"],"pubmed_title":["Experimental Infection of North American Sheep with Ehrlichia ruminantium."],"pmcid":["PMC8070521"],"pubmed_authors":["Liu H","Ganta CK","Hove P","Henningson J","Ganta RR","Wang Y","Cino-Ozuna AG","Nair A"],"additional_accession":[]},"is_claimable":false,"name":"Experimental Infection of North American Sheep with Ehrlichia ruminantium.","description":"Ehrlichia ruminantium, a tick-borne rickettsial, causes heartwater in ruminants resulting from vascular damage. Severity of heartwater varies greatly in ruminant species and breeds, age of animals and for diverse geographic E. ruminantium strains. E. ruminantium and a tick vector, Amblyomma variegatum, originating from Africa, are well established in certain Caribbean islands two centuries ago. Besides the possibility of introduction of heartwater through African exotic animal importation, presence of the pathogen, and the tick vector in the Caribbean pose a high risk to ruminants in the USA and other western hemisphere countries. Scientific evidence supporting the heartwater threat to nonendemic regions, however, is lacking. We describe the first infection study in sheep reared in the USA","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Apr","modification":"2025-04-06T22:51:32.743Z","creation":"2025-04-04T07:19:26.188Z"},"accession":"S-EPMC8070521","cross_references":{"pubmed":["33918856"],"doi":["10.3390/pathogens10040451"]}}