{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Fan Y"],"funding":["Natural Science Foundation of Henan Province","Foundation of Henan Polytechnic University"],"pagination":["2322"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8073518"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["26(8)"],"pubmed_abstract":["Baicalin which has multiple biological activities is the main active component of the root of <i>Scutellaria baicalensis</i> Georgi (SBG). Although its isolation and purification by adsorption methods have aroused much interest of the scientific community, it suffered from the poor selectivity of the adsorbents. In this work, an environmentally benign method was developed to prepare ionic liquids (ILs) grafted silica by using IL 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ([C<sub>4</sub>mim]NTf<sub>2</sub>) and ethanol as reaction media. The IL 1-propyl-3-methylimidazolium chloride ([C<sub>3</sub>mim]Cl) grafted silica ([C<sub>3</sub>mim]<sup>+</sup>Cl<sup>-</sup>@SiO<sub>2</sub>) was used to adsorb and purify baicalin from the root extract of <i>Scutellaria baicalensis</"],"journal":["Molecules (Basel, Switzerland)"],"pubmed_title":["Adsorption and Purification of Baicalin from <i>Scutellaria baicalensis</i> Georgi Extract by Ionic Liquids (ILs) Grafted Silica."],"pmcid":["PMC8073518"],"funding_grant_id":["182102310728","NSFRF200313"],"pubmed_authors":["Fan Y","Wu D","Zhang S"],"additional_accession":[]},"is_claimable":false,"name":"Adsorption and Purification of Baicalin from <i>Scutellaria baicalensis</i> Georgi Extract by Ionic Liquids (ILs) Grafted Silica.","description":"Baicalin which has multiple biological activities is the main active component of the root of <i>Scutellaria baicalensis</i> Georgi (SBG). Although its isolation and purification by adsorption methods have aroused much interest of the scientific community, it suffered from the poor selectivity of the adsorbents. In this work, an environmentally benign method was developed to prepare ionic liquids (ILs) grafted silica by using IL 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide ([C<sub>4</sub>mim]NTf<sub>2</sub>) and ethanol as reaction media. The IL 1-propyl-3-methylimidazolium chloride ([C<sub>3</sub>mim]Cl) grafted silica ([C<sub>3</sub>mim]<sup>+</sup>Cl<sup>-</sup>@SiO<sub>2</sub>) was used to adsorb and purify baicalin from the root extract of <i>Scutellaria baicalensis</","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Apr","modification":"2026-07-09T11:28:59.312Z","creation":"2022-02-09T18:12:20.567Z"},"accession":"S-EPMC8073518","cross_references":{"pubmed":["33923637"],"doi":["10.3390/molecules26082322"]}}