biostudies-literatureUnknown30(5)Ngo BTThe Rose Salter Medical Research FoundationBackground: COVID-19 has several overlapping phases. Treatments to date have focused on the late stage of disease in hospital. Yet, the pandemic is by propagated by the viral phase in out-patients. The current public health strategy relies solely on vaccines to prevent disease.Methods: We searched the major national registries, pubmed.org, and the preprint servers for all ongoing, completed and published trial results.Results: As of 2/15/2021, we found 111 publications reporting findings on 14 classes of agents, and 9 vaccines. There were 62 randomized controlled studies, the rest retrospective observational analyses. Only 21 publications dealt with outpatient care. Remdesivir and high titer convalescent plasma have emergency use authorization for hospitalized patientsExpert opinion on investigational drugs505-518https://www.ebi.ac.uk/biostudies/studies/S-EPMC8074648biostudies-literatureThe time to offer treatments for COVID-19.PMC8074648Chaudhary PHanna DLBello Rivero INgo BTSmogorewski MVaron JDube MPeschanski NThomadsen RGriffin DConfalonieri MIn GNanda NArmstrong AHayem GSoriano VVinjevoll EHDitmore SBrennan-Rieder DMitja OSawcer DEArkfeld DTurkia MIglesias JDasgupta RShapiro LMarik PPiccirillo MCHung IFPeng DKory PLobo-Ferreira AEhresmann GSattler FMussini CCampese VMRendell MfalseThe time to offer treatments for COVID-19.Background: COVID-19 has several overlapping phases. Treatments to date have focused on the late stage of disease in hospital. Yet, the pandemic is by propagated by the viral phase in out-patients. The current public health strategy relies solely on vaccines to prevent disease.Methods: We searched the major national registries, pubmed.org, and the preprint servers for all ongoing, completed and published trial results.Results: As of 2/15/2021, we found 111 publications reporting findings on 14 classes of agents, and 9 vaccines. There were 62 randomized controlled studies, the rest retrospective observational analyses. Only 21 publications dealt with outpatient care. Remdesivir and high titer convalescent plasma have emergency use authorization for hospitalized patients2021-01-01T00:00:00Z2021 May2026-04-19T03:21:03.488Z2022-02-11T14:32:19.35ZS-EPMC80746483372154810.1080/13543784.2021.1901883