biostudies-literatureLuo LNHLBI NIH HHSe24818https://www.ebi.ac.uk/biostudies/studies/S-EPMC8087964biostudies-literatureUnknown10(4)<h4>Background</h4>Individuals living with sickle cell disease often require aggressive treatment of pain associated with vaso-occlusive episodes in the emergency department. Frequently, pain relief is poor. The 2014 National Heart, Lung, and Blood Institute evidence-based guidelines recommended an individualized treatment and monitoring protocol to improve pain management of vaso-occlusive episodes.<h4>Objective</h4>This study will implement an electronic health record-embedded individualized pain plan with provider and patient access in the emergency departments of 8 US academic centers to improve pain treatment for adult patients with sickle cell disease. This study will assess the overall effects of electronic health record-embedded individualized pain plans on improving patient and prJMIR research protocolsElectronic Health Record-Embedded Individualized Pain Plans for Emergency Department Treatment of Vaso-occlusive Episodes in Adults With Sickle Cell Disease: Protocol for a Preimplementation and Postimplementation Study.PMC8087964U01 HL133990U01 HL134042U01 HL133964U01 HL133997U24 HL133948U01 HL134004U01 HL133994U01 HL134007U01 HL133996Klesges LSiewny LRichardson LDKutlar AGollan SMelvin CLBaumann AAPotter MBHall GTanabe PArmstrong-Brown JBrambilla DColla JCarroll YKing AALyon MZun LMueller MLuo LCarpenter CRGibson RWRichesson RTreadwell MCox LNorell SRyan GfalseElectronic Health Record-Embedded Individualized Pain Plans for Emergency Department Treatment of Vaso-occlusive Episodes in Adults With Sickle Cell Disease: Protocol for a Preimplementation and Postimplementation Study.<h4>Background</h4>Individuals living with sickle cell disease often require aggressive treatment of pain associated with vaso-occlusive episodes in the emergency department. Frequently, pain relief is poor. The 2014 National Heart, Lung, and Blood Institute evidence-based guidelines recommended an individualized treatment and monitoring protocol to improve pain management of vaso-occlusive episodes.<h4>Objective</h4>This study will implement an electronic health record-embedded individualized pain plan with provider and patient access in the emergency departments of 8 US academic centers to improve pain treatment for adult patients with sickle cell disease. This study will assess the overall effects of electronic health record-embedded individualized pain plans on improving patient and pr2021-01-01T00:00:00Z2021 Apr2026-05-08T13:26:40.18Z2022-02-10T09:32:59.98ZS-EPMC80879643386120910.2196/24818