{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["27(5)"],"submitter":["Jacobs KM"],"pubmed_abstract":["<h4>Objective</h4>Multiple studies show cultivatable bacteria in urine of most women. The existence of these bacteria challenges interstitial cystitis (IC)/painful bladder syndrome (PBS) diagnosis, which presumes a sterile bladder. The aims of this study were (1) to compare the female bladder microbiomes in women with IC/PBS and unaffected controls and (2) to correlate baseline bladder microbiome composition with symptoms.<h4>Methods</h4>This cross-sectional study enrolled 49 IC/PBS and 40 controls. All provided catheterized urine samples and completed validated questionnaires. A subset of the IC/PBS cohort provided voided and catheterized urine samples. All samples from both cohorts were assessed by the expanded quantitative urine culture (EQUC) protocol; a subset was assessed by 16S rRNA"],"journal":["Female pelvic medicine & reconstructive surgery"],"pagination":["322-327"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8088819"],"repository":["biostudies-literature"],"pubmed_title":["Cultivable Bacteria in Urine of Women With Interstitial Cystitis: (Not) What We Expected."],"pmcid":["PMC8088819"],"pubmed_authors":["Halverson T","Davies A","Wolfe AJ","Jacobs KM","Thomas-White K","Price TK","Myers DL"],"additional_accession":[]},"is_claimable":false,"name":"Cultivable Bacteria in Urine of Women With Interstitial Cystitis: (Not) What We Expected.","description":"<h4>Objective</h4>Multiple studies show cultivatable bacteria in urine of most women. The existence of these bacteria challenges interstitial cystitis (IC)/painful bladder syndrome (PBS) diagnosis, which presumes a sterile bladder. The aims of this study were (1) to compare the female bladder microbiomes in women with IC/PBS and unaffected controls and (2) to correlate baseline bladder microbiome composition with symptoms.<h4>Methods</h4>This cross-sectional study enrolled 49 IC/PBS and 40 controls. All provided catheterized urine samples and completed validated questionnaires. A subset of the IC/PBS cohort provided voided and catheterized urine samples. All samples from both cohorts were assessed by the expanded quantitative urine culture (EQUC) protocol; a subset was assessed by 16S rRNA","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 May","modification":"2025-04-04T07:20:17.355Z","creation":"2025-04-04T07:20:17.355Z"},"accession":"S-EPMC8088819","cross_references":{"pubmed":["32265402"],"doi":["10.1097/SPV.0000000000000854"]}}