{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["5(Suppl 1)"],"submitter":["Bruno B"],"pubmed_abstract":["Abstract Male hypogonadism is characterized by symptoms and deficiency (<300 ng/dL) in levels of in total testosterone (TT), a critical hormone for sexual, cognitive, and body function and development. TLANDO, a testosterone undecanoate (TU) comprising lymphatically delivered oral testosterone replacement therapy (TRT) option not requiring dose titration, treatment has demonstrated effective restoration in hypogonadal men of TT levels to the eugonadal range in multiple clinical studies. TLANDO therapy resulted in decreased sex hormone binding globulin with increased free testosterone (FT). TLANDO’s unique delivery system enables consistent restoration of TT regardless of meal fat content. Moreover, TLANDO has shown potential to improve liver health through resolution of fatty liver disease"],"journal":["Journal of the Endocrine Society"],"pagination":["A495-A496"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8090604"],"repository":["biostudies-literature"],"pubmed_title":["TLANDO, a Novel Oral TRT, Improves Sexual and Mental Domain Outcomes in Hypogonadal Men"],"pmcid":["PMC8090604"],"pubmed_authors":["Bruno B","Papangkorn K","Carson III C","Miner M","Kim K","DelConte A","Kaminetsky J","Vangara K","Goldstein I","Khera M","Patel M","Chidambaram N"],"additional_accession":[]},"is_claimable":false,"name":"TLANDO, a Novel Oral TRT, Improves Sexual and Mental Domain Outcomes in Hypogonadal Men","description":"Abstract Male hypogonadism is characterized by symptoms and deficiency (<300 ng/dL) in levels of in total testosterone (TT), a critical hormone for sexual, cognitive, and body function and development. TLANDO, a testosterone undecanoate (TU) comprising lymphatically delivered oral testosterone replacement therapy (TRT) option not requiring dose titration, treatment has demonstrated effective restoration in hypogonadal men of TT levels to the eugonadal range in multiple clinical studies. TLANDO therapy resulted in decreased sex hormone binding globulin with increased free testosterone (FT). TLANDO’s unique delivery system enables consistent restoration of TT regardless of meal fat content. Moreover, TLANDO has shown potential to improve liver health through resolution of fatty liver disease","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 May","modification":"2025-04-22T17:54:09.351Z","creation":"2022-02-10T18:53:36.757Z"},"accession":"S-EPMC8090604","cross_references":{}}