{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Wang X"],"funding":["National Institute of Environmental Health Sciences","NIA NIH HHS","NCRR NIH HHS","National Institute of Nursing Research","NIEHS NIH HHS","NHLBI NIH HHS","National Heart, Lung, and Blood Institute","National Institute on Aging","NIDDK NIH HHS","ACL HHS","National Institute for Occupational Safety and Health","NIOSH CDC HHS","NINR NIH HHS"],"pagination":["110426"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8093324"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["196"],"pubmed_abstract":["Background
Information on the associations between metal exposures and adipokines in human populations is limited and results are inconsistent. We evaluated the associations between metals and adipokines.Methods
Urinary concentrations of 15 metals (arsenic, barium, cadmium, cobalt, cesium, copper, mercury, manganese, molybdenum, nickel, lead, antimony, tin, thallium, and zinc) were measured in 1999-2000 among 1228 women of the Study of Women's Health Across the Nation Multi-Pollutant Study. Serum adipokines including high molecular weight (HMW)-adiponectin, leptin, and soluble leptin receptor (sOB-R) were measured at the follow-up visit (2002-2003). Linear regression models with adaptive elastic-net (AENET) were fit to identify metals associated with adipokines and to compu"],"journal":["Environmental research"],"pubmed_title":["Urinary metals and adipokines in midlife women: The Study of Women's Health Across the nation (SWAN)."],"pmcid":["PMC8093324"],"funding_grant_id":["U01 AG012554","R01 ES026578","U01 AG012553","U01 AG012531","P30 DK092926","R01 ES026964","U01 AG012535","U01 AG012546","U01 AG012539","T42 OH008455","U01 AG012505","R21 HL091290","U01 AG017719","P30 ES017885","P30 DK020572","U19 AG063720","U01 AG012495","U01 NR004061","UL1 RR024131","T42OH008455"],"pubmed_authors":["Karvonen-Gutierrez CA","Mukherjee B","Herman WH","Wang X","Park SK"],"additional_accession":[]},"is_claimable":false,"name":"Urinary metals and adipokines in midlife women: The Study of Women's Health Across the nation (SWAN).","description":"Background
Information on the associations between metal exposures and adipokines in human populations is limited and results are inconsistent. We evaluated the associations between metals and adipokines.Methods
Urinary concentrations of 15 metals (arsenic, barium, cadmium, cobalt, cesium, copper, mercury, manganese, molybdenum, nickel, lead, antimony, tin, thallium, and zinc) were measured in 1999-2000 among 1228 women of the Study of Women's Health Across the Nation Multi-Pollutant Study. Serum adipokines including high molecular weight (HMW)-adiponectin, leptin, and soluble leptin receptor (sOB-R) were measured at the follow-up visit (2002-2003). Linear regression models with adaptive elastic-net (AENET) were fit to identify metals associated with adipokines and to compu","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 May","modification":"2025-04-04T10:15:51.444Z","creation":"2025-04-04T10:15:51.444Z"},"accession":"S-EPMC8093324","cross_references":{"pubmed":["33157106"],"doi":["10.1016/j.envres.2020.110426"]}}