biostudies-literatureUnknown175(7)Lonsdale C<h4>Importance</h4>Cardiorespiratory fitness is an important marker of childhood health and low fitness levels are a risk factor for disease later in life. Levels of children's fitness have declined in recent decades. Whether school-based physical activity interventions can increase fitness at the population level remains unclear.<h4>Objective</h4>To evaluate the effect of an internet-based intervention on children's cardiorespiratory fitness across a large number of schools.<h4>Design, setting, and participants</h4>In this cluster randomized clinical trial, 22 government-funded elementary schools (from 137 providing consent) including 1188 students stratified from grades 3 and 4 in New South Wales, Australia, were randomized. The other schools received the intervention but were not included in the analysis. Eleven schools received the internet-based intervention and 11 received the control intervention. Recruitment and baseline testing began in 2016 and ended in 2017. Research assistants, blinded to treatment allocation, completed follow-up outcome assessments at 12 and 24 months. Data were analyzed from July to August 2020.<h4>Interventions</h4>The internet-based intervention included standardized online learning for teachers and minimal in-person support from a project mentor (9-10 months).<h4>Main outcomes and measures</h4>Multistage 20-m shuttle run test for cardiorespiratory fitness.<h4>Results</h4>Of 1219 participants (49% girls; mean [SD] age, 8.85 [0.71] years) from 22 schools, 1188 students provided baseline primary outcome data. At 12 months, the number of 20-m shuttle runs increased by 3.32 laps (95% CI, 2.44-4.20 laps) in the intervention schools and 2.11 laps (95% CI, 1.38-2.85 laps) in the control schools (adjusted difference = 1.20 laps; 95% CI, 0.17-2.24 laps). By 24 months, the adjusted difference was 2.22 laps (95% CI, 0.89-3.55 laps). The cost per student was AUD33 (USD26).<h4>Conclusions and relevance</h4>In this study, a school-based intervention improved children's cardiorespiratory fitness when delivered in a large number of schools. The low cost and sustained effect over 24 months of the intervention suggests that it may have potential to be scaled at the population level.<h4>Trial registration</h4>http://anzctr.org.au Identifier: ACTRN12616000731493.JAMA pediatrics680-688https://www.ebi.ac.uk/biostudies/studies/S-EPMC8094033biostudies-literatureEffect of a Scalable School-Based Intervention on Cardiorespiratory Fitness in Children: A Cluster Randomized Clinical Trial.PMC8094033Antczak DSalmon JLubans DRLee JHillman CHartwig TMoodie MMcKay HGreene DParker PCinelli RLonsdale CGore JBoyer JCliff DShigeta TTVasconcellos DTan EPeralta LSanders TKirwan MBennie AGao LMorrison RPlotnikoff RCKolt GMorgan PNoetel MfalseEffect of a Scalable School-Based Intervention on Cardiorespiratory Fitness in Children: A Cluster Randomized Clinical Trial.<h4>Importance</h4>Cardiorespiratory fitness is an important marker of childhood health and low fitness levels are a risk factor for disease later in life. Levels of children's fitness have declined in recent decades. Whether school-based physical activity interventions can increase fitness at the population level remains unclear.<h4>Objective</h4>To evaluate the effect of an internet-based intervention on children's cardiorespiratory fitness across a large number of schools.<h4>Design, setting, and participants</h4>In this cluster randomized clinical trial, 22 government-funded elementary schools (from 137 providing consent) including 1188 students stratified from grades 3 and 4 in New South Wales, Australia, were randomized. The other schools received the intervention but were not included in the analysis. Eleven schools received the internet-based intervention and 11 received the control intervention. Recruitment and baseline testing began in 2016 and ended in 2017. Research assistants, blinded to treatment allocation, completed follow-up outcome assessments at 12 and 24 months. Data were analyzed from July to August 2020.<h4>Interventions</h4>The internet-based intervention included standardized online learning for teachers and minimal in-person support from a project mentor (9-10 months).<h4>Main outcomes and measures</h4>Multistage 20-m shuttle run test for cardiorespiratory fitness.<h4>Results</h4>Of 1219 participants (49% girls; mean [SD] age, 8.85 [0.71] years) from 22 schools, 1188 students provided baseline primary outcome data. At 12 months, the number of 20-m shuttle runs increased by 3.32 laps (95% CI, 2.44-4.20 laps) in the intervention schools and 2.11 laps (95% CI, 1.38-2.85 laps) in the control schools (adjusted difference = 1.20 laps; 95% CI, 0.17-2.24 laps). By 24 months, the adjusted difference was 2.22 laps (95% CI, 0.89-3.55 laps). The cost per student was AUD33 (USD26).<h4>Conclusions and relevance</h4>In this study, a school-based intervention improved children's cardiorespiratory fitness when delivered in a large number of schools. The low cost and sustained effect over 24 months of the intervention suggests that it may have potential to be scaled at the population level.<h4>Trial registration</h4>http://anzctr.org.au Identifier: ACTRN12616000731493.2021-01-01T00:00:00Z2021 Jul2025-04-04T10:16:09.142Z2025-04-04T10:16:09.142ZS-EPMC80940333393894610.1001/jamapediatrics.2021.0417