{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["11(1)"],"submitter":["Beddok A"],"funding":["Department of Clinical Research, Amiens University Hospital, France"],"pubmed_abstract":["Soft tissue sarcoma represents about 1% of all adult cancers. Occurrence of multiple sarcomas in a same individual cannot be fortuitous. A 72-year-old patient had between 2007 and 2016 a glomangiopericytal tumor of the right forearm and a succession of sarcomas of the extremities: a leiomyosarcoma of the left buttock, a myxofibrosarcoma (MFS) of the right forearm, a MFS of the left scapula, a left latero-thoracic MFS and two undifferentiated sarcomas on the left forearm. Pathological examination of the six locations was not in favor of disease with local/distant recurrences but could not confirm different diseases. An extensive molecular analysis including DNA-array, RNA-sequencing and DNA-Sanger-sequencing, was thus performed to determine the link between them. The genomic profile of the "],"journal":["Scientific reports"],"pagination":["9765"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8105326"],"repository":["biostudies-literature"],"pubmed_title":["Germinal GLT8D1, GATAD2A and SLC25A39 mutations in a patient with a glomangiopericytal tumor and five different sarcomas over a 10-year period."],"pmcid":["PMC8105326"],"pubmed_authors":["Thebault N","Chauffert B","Sevestre H","Beddok A","Le Guellec S","Perot G","Coutte A","Chibon F"],"additional_accession":[]},"is_claimable":false,"name":"Germinal GLT8D1, GATAD2A and SLC25A39 mutations in a patient with a glomangiopericytal tumor and five different sarcomas over a 10-year period.","description":"Soft tissue sarcoma represents about 1% of all adult cancers. Occurrence of multiple sarcomas in a same individual cannot be fortuitous. A 72-year-old patient had between 2007 and 2016 a glomangiopericytal tumor of the right forearm and a succession of sarcomas of the extremities: a leiomyosarcoma of the left buttock, a myxofibrosarcoma (MFS) of the right forearm, a MFS of the left scapula, a left latero-thoracic MFS and two undifferentiated sarcomas on the left forearm. Pathological examination of the six locations was not in favor of disease with local/distant recurrences but could not confirm different diseases. An extensive molecular analysis including DNA-array, RNA-sequencing and DNA-Sanger-sequencing, was thus performed to determine the link between them. The genomic profile of the ","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 May","modification":"2026-04-18T05:30:06.828Z","creation":"2022-02-10T09:51:23.753Z"},"accession":"S-EPMC8105326","cross_references":{"pubmed":["33963205"],"doi":["10.1038/s41598-021-88671-0"]}}