{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["21(1)"],"submitter":["Tran L"],"pubmed_abstract":["<h4>Background</h4>Systematic reviews (SRs) and meta-analyses (MAs) are commonly conducted to evaluate and summarize medical literature. This is especially useful in assessing in vitro studies for consistency. Our study aims to systematically review all available quality assessment (QA) tools employed on in vitro SRs/MAs.<h4>Method</h4>A search on four databases, including PubMed, Scopus, Virtual Health Library and Web of Science, was conducted from 2006 to 2020. The available SRs/MAs of in vitro studies were evaluated. DARE tool was applied to assess the risk of bias of included articles. Our protocol was developed and uploaded to ResearchGate in June 2016.<h4>Results</h4>Our findings reported an increasing trend in publication of in vitro SRs/MAs from 2007 to 2020. Among the 244 included"],"journal":["BMC medical research methodology"],"pagination":["101"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8106836"],"repository":["biostudies-literature"],"pubmed_title":["Quality assessment tools used in systematic reviews of in vitro studies: A systematic review."],"pmcid":["PMC8106836"],"pubmed_authors":["Elshafay A","Hirayama K","Dang T","Tran L","Tam DNH","Huy NT"],"additional_accession":[]},"is_claimable":false,"name":"Quality assessment tools used in systematic reviews of in vitro studies: A systematic review.","description":"<h4>Background</h4>Systematic reviews (SRs) and meta-analyses (MAs) are commonly conducted to evaluate and summarize medical literature. This is especially useful in assessing in vitro studies for consistency. Our study aims to systematically review all available quality assessment (QA) tools employed on in vitro SRs/MAs.<h4>Method</h4>A search on four databases, including PubMed, Scopus, Virtual Health Library and Web of Science, was conducted from 2006 to 2020. The available SRs/MAs of in vitro studies were evaluated. DARE tool was applied to assess the risk of bias of included articles. Our protocol was developed and uploaded to ResearchGate in June 2016.<h4>Results</h4>Our findings reported an increasing trend in publication of in vitro SRs/MAs from 2007 to 2020. Among the 244 included","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 May","modification":"2026-07-16T07:47:07.937Z","creation":"2026-07-09T10:46:02.39Z"},"accession":"S-EPMC8106836","cross_references":{"pubmed":["33964880"],"doi":["10.1186/s12874-021-01295-w"]}}