{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["29(2)"],"submitter":["Gupta RK"],"pubmed_abstract":["<h4>Background and purpose</h4>Neuroinflammatory molecules, including tumor necrosis factor-alpha, interleukin1-beta, lymphocyte function associated molecule-1, and intercellular cell adhesion molecule-1 contribute to the development of brain abscess. We hypothesized that the high fractional anisotropy (FA) in the brain abscess cavity reflects the upregulation of these neuroinflammatory molecules.<h4>Materials and methods</h4>Diffusion tensor imaging (DTI) was performed in 24 patients with brain abscess and Staphylococcus aureus-treated as well as nontreated Jurket cell lines (at 4 time points: 1, 24, 48, and 72 hours). Neuroinflammatory molecules were quantified from the brain abscess cavity aspirate of the patients as well as from the heat-killed S aureus-treated and nontreated cell line"],"journal":["AJNR. American journal of neuroradiology"],"pagination":["326-32"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8118972"],"repository":["biostudies-literature"],"pubmed_title":["In vivo demonstration of neuroinflammatory molecule expression in brain abscess with diffusion tensor imaging."],"pmcid":["PMC8118972"],"pubmed_authors":["Gupta RK","Srivastava C","Khetan P","Trivedi R","Prasad A","Narayana PA","Nath K","Rathore RK","Prasad KN","Husain N","Husain M"],"additional_accession":[]},"is_claimable":false,"name":"In vivo demonstration of neuroinflammatory molecule expression in brain abscess with diffusion tensor imaging.","description":"<h4>Background and purpose</h4>Neuroinflammatory molecules, including tumor necrosis factor-alpha, interleukin1-beta, lymphocyte function associated molecule-1, and intercellular cell adhesion molecule-1 contribute to the development of brain abscess. We hypothesized that the high fractional anisotropy (FA) in the brain abscess cavity reflects the upregulation of these neuroinflammatory molecules.<h4>Materials and methods</h4>Diffusion tensor imaging (DTI) was performed in 24 patients with brain abscess and Staphylococcus aureus-treated as well as nontreated Jurket cell lines (at 4 time points: 1, 24, 48, and 72 hours). Neuroinflammatory molecules were quantified from the brain abscess cavity aspirate of the patients as well as from the heat-killed S aureus-treated and nontreated cell line","dates":{"release":"2008-01-01T00:00:00Z","publication":"2008 Feb","modification":"2025-04-26T07:21:58.302Z","creation":"2022-02-10T10:01:50.403Z"},"accession":"S-EPMC8118972","cross_references":{"pubmed":["17989372"],"doi":["10.3174/ajnr.A0826","10.3174/ajnr.a0826"]}}