{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["2021"],"submitter":["Zhang S"],"pubmed_abstract":["Chinese herbal Fu-Zheng-Qu-Xie (FZQX) prescription has been found to improve the immune function and survival of patients with early-stage lung cancer. However, the therapeutic efficacy needs to be evaluated objectively, and the precise mechanism remains unclear. In the present study, a double-center, prospective cohort study was carried out to assess the clinical efficacy of the FZQX prescription in preventing the recurrence and metastasis of postoperative early-stage lung adenocarcinoma. Our results indicated that the FZQX prescription could significantly reduce the 3-year postoperative recurrence rate and improve the life quality. Moreover, the peripheral blood indices showed that the positive immune index (CD<sub>4</sub> <sup>+</sup>T/CD<sub>8</sub> <sup>+</sup>T) increased and the neg"],"journal":["Oxidative medicine and cellular longevity"],"pagination":["6673828"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8133853"],"repository":["biostudies-literature"],"pubmed_title":["Chinese Herbal Prescription Fu-Zheng-Qu-Xie Prevents Recurrence and Metastasis of Postoperative Early-Stage Lung Adenocarcinoma: A Prospective Cohort Study Followed with Potential Mechanism Exploration."],"pmcid":["PMC8133853"],"pubmed_authors":["Xu L","Tian J","Wu J","Li Y","Fang Z","Jiang L","Xu R","Chen W","Luo Y","Zhang S","Wang Y","Yu Y"],"additional_accession":[]},"is_claimable":false,"name":"Chinese Herbal Prescription Fu-Zheng-Qu-Xie Prevents Recurrence and Metastasis of Postoperative Early-Stage Lung Adenocarcinoma: A Prospective Cohort Study Followed with Potential Mechanism Exploration.","description":"Chinese herbal Fu-Zheng-Qu-Xie (FZQX) prescription has been found to improve the immune function and survival of patients with early-stage lung cancer. However, the therapeutic efficacy needs to be evaluated objectively, and the precise mechanism remains unclear. In the present study, a double-center, prospective cohort study was carried out to assess the clinical efficacy of the FZQX prescription in preventing the recurrence and metastasis of postoperative early-stage lung adenocarcinoma. Our results indicated that the FZQX prescription could significantly reduce the 3-year postoperative recurrence rate and improve the life quality. Moreover, the peripheral blood indices showed that the positive immune index (CD<sub>4</sub> <sup>+</sup>T/CD<sub>8</sub> <sup>+</sup>T) increased and the neg","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021","modification":"2025-04-18T14:55:25.47Z","creation":"2022-02-10T12:57:57.563Z"},"accession":"S-EPMC8133853","cross_references":{"pubmed":["34055197"],"doi":["10.1155/2021/6673828"]}}