{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Liu C"],"funding":["Innovative Research Group Project of the National Natural Science Foundation of China","the Strategic Priority Research Program of Chinese Academy of Sciences"],"pagination":["119"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8140505"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["9(1)"],"pubmed_abstract":["Background
In gut microbiome studies, the cultured gut microbial resource plays essential roles, such as helping to unravel gut microbial functions and host-microbe interactions. Although several major studies have been performed to elucidate the cultured human gut microbiota, up to 70% of the Unified Human Gastrointestinal Genome species have not been cultured to date. Large-scale gut microbial isolation and identification as well as availability to the public are imperative for gut microbial studies and further characterizing human gut microbial functions.Results
In this study, we constructed a human Gut Microbial Biobank (hGMB; homepage: hgmb.nmdc.cn ) through the cultivation of 10,558 isolates from 31 sample mixtures of 239 fresh fecal samples from healthy Chinese volun"],"journal":["Microbiome"],"pubmed_title":["Enlightening the taxonomy darkness of human gut microbiomes with a cultured biobank."],"pmcid":["PMC8140505"],"funding_grant_id":["XDB38020300","2019YFA0905601"],"pubmed_authors":["Shi WY","Zhou N","Wu L","Du MX","Chen HH","Zhou Y","Han SS","Yu HY","Wang YJ","Liu SJ","Jiang CY","Xin YH","Li DH","Niu PX","Jiang MZ","Ma J","Liu HW","Liu C","Abuduaini R"],"additional_accession":[]},"is_claimable":false,"name":"Enlightening the taxonomy darkness of human gut microbiomes with a cultured biobank.","description":"Background
In gut microbiome studies, the cultured gut microbial resource plays essential roles, such as helping to unravel gut microbial functions and host-microbe interactions. Although several major studies have been performed to elucidate the cultured human gut microbiota, up to 70% of the Unified Human Gastrointestinal Genome species have not been cultured to date. Large-scale gut microbial isolation and identification as well as availability to the public are imperative for gut microbial studies and further characterizing human gut microbial functions.Results
In this study, we constructed a human Gut Microbial Biobank (hGMB; homepage: hgmb.nmdc.cn ) through the cultivation of 10,558 isolates from 31 sample mixtures of 239 fresh fecal samples from healthy Chinese volun","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 May","modification":"2026-04-12T15:45:21.239Z","creation":"2022-02-10T15:20:21.373Z"},"accession":"S-EPMC8140505","cross_references":{"pubmed":["34020714"],"doi":["10.1186/s40168-021-01064-3"]}}