{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Kalmbach DA"],"funding":["NHLBI NIH HHS","American Academy of Sleep Medicine","National Heart Lung and Blood Institute"],"pagination":["439-442"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8142329"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["81"],"pubmed_abstract":["<h4>Objectives</h4>This prospective study explored associations among insomnia, nocturnal cognitive hyperarousal, and nocturnal perinatal-focused rumination with suicidal ideation (SI) in perinatal women with depression.<h4>Methods</h4>From late pregnancy through early postpartum, 39 depressed women completed 17 weekly surveys assessing SI, insomnia, depression, stress, and cognitive arousal.<h4>Results</h4>Women with nocturnal cognitive hyperarousal at baseline, relative to those with low cognitive arousal, were at greater risk for new onset SI (33% vs 1%). Moreover, nocturnal perinatal-focused rumination was independently associated with SI. SI-risk was highest when women reported clinical insomnia combined with nocturnal cognitive hyperarousal (OR = 5.66, p = 0.037) or perinatal-focused"],"journal":["Sleep medicine"],"pubmed_title":["Nocturnal cognitive hyperarousal, perinatal-focused rumination, and insomnia are associated with suicidal ideation in perinatal women with mild to moderate depression."],"pmcid":["PMC8142329"],"funding_grant_id":["K23 HL138166"],"pubmed_authors":["Gelaye B","Drake CL","Cheng P","Ahmedani BK","Kalmbach DA"],"additional_accession":[]},"is_claimable":false,"name":"Nocturnal cognitive hyperarousal, perinatal-focused rumination, and insomnia are associated with suicidal ideation in perinatal women with mild to moderate depression.","description":"<h4>Objectives</h4>This prospective study explored associations among insomnia, nocturnal cognitive hyperarousal, and nocturnal perinatal-focused rumination with suicidal ideation (SI) in perinatal women with depression.<h4>Methods</h4>From late pregnancy through early postpartum, 39 depressed women completed 17 weekly surveys assessing SI, insomnia, depression, stress, and cognitive arousal.<h4>Results</h4>Women with nocturnal cognitive hyperarousal at baseline, relative to those with low cognitive arousal, were at greater risk for new onset SI (33% vs 1%). Moreover, nocturnal perinatal-focused rumination was independently associated with SI. SI-risk was highest when women reported clinical insomnia combined with nocturnal cognitive hyperarousal (OR = 5.66, p = 0.037) or perinatal-focused","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 May","modification":"2025-04-05T10:03:19.055Z","creation":"2025-04-05T10:03:19.055Z"},"accession":"S-EPMC8142329","cross_references":{"pubmed":["33839373"],"doi":["10.1016/j.sleep.2021.03.004"]}}