{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Guo L"],"funding":["Key Technology Research and Development Program of Shandong","Natural Science Foundation of Shandong Province","National Natural Science Foundation of China"],"pagination":["2407-2413"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8157567"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["11(9)"],"pubmed_abstract":["In this study, a novel lanthanide-doped nanoprobe for monitoring dipicolinic acid (DPA), a unique biomarker of <i>Bacillus anthracis</i>, was constructed by coordination of Tb<sup>3+</sup> with l-histidine (His) functionalized ZIF-8 (His@ZIF-8). After being functionalized with His, the resultant His@ZIF-8 had abundant carboxyl and amino groups, which like tongs help His@ZIF-8 \"grasp\" Tb<sup>3+</sup> firmly to form a stable lanthanide-doped nanoparticle (His@ZIF-8/Tb<sup>3+</sup>). Owing to the unsaturated coordination of Tb<sup>3+</sup> with the amino acid group, the resultant His@ZIF-8/Tb<sup>3+</sup> showed reserved response sites of Tb<sup>3+</sup> to DPA because of its unique molecular structure. After the His@ZIF-8/Tb<sup>3+</sup> coordination with DPA, the intrinsic fluorescence emis"],"journal":["Chemical science"],"pubmed_title":["The role of l-histidine as molecular tongs: a strategy of grasping Tb<sup>3+</sup> using ZIF-8 to design sensors for monitoring an anthrax biomarker on-the-spot."],"pmcid":["PMC8157567"],"funding_grant_id":["ZR2013BQ019","2017GSF19109","ZR2014BM029","21505084","21475074","21775089"],"pubmed_authors":["Guo L","Kong R","Xia L","Chen G","Liang M","Wang X","Qu F"],"additional_accession":[]},"is_claimable":false,"name":"The role of l-histidine as molecular tongs: a strategy of grasping Tb<sup>3+</sup> using ZIF-8 to design sensors for monitoring an anthrax biomarker on-the-spot.","description":"In this study, a novel lanthanide-doped nanoprobe for monitoring dipicolinic acid (DPA), a unique biomarker of <i>Bacillus anthracis</i>, was constructed by coordination of Tb<sup>3+</sup> with l-histidine (His) functionalized ZIF-8 (His@ZIF-8). After being functionalized with His, the resultant His@ZIF-8 had abundant carboxyl and amino groups, which like tongs help His@ZIF-8 \"grasp\" Tb<sup>3+</sup> firmly to form a stable lanthanide-doped nanoparticle (His@ZIF-8/Tb<sup>3+</sup>). Owing to the unsaturated coordination of Tb<sup>3+</sup> with the amino acid group, the resultant His@ZIF-8/Tb<sup>3+</sup> showed reserved response sites of Tb<sup>3+</sup> to DPA because of its unique molecular structure. After the His@ZIF-8/Tb<sup>3+</sup> coordination with DPA, the intrinsic fluorescence emis","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Jan","modification":"2025-04-18T13:43:04.903Z","creation":"2022-02-10T13:33:13.273Z"},"accession":"S-EPMC8157567","cross_references":{"pubmed":["34084404"],"doi":["10.1039/d0sc00030b"]}}