{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Lai HH"],"funding":["NIDDK NIH HHS","National Institute of Diabetes and Digestive and Kidney Diseases"],"pagination":["810-818"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8159180"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["40(3)"],"pubmed_abstract":["<h4>Objective</h4>To use the phenotyping data from the MAPP-II Symptom Patterns Study (SPS) to compare the systemic features between urologic chronic pelvic pain syndrome (UCPPS) with Hunner lesion (HL) versus those without HL.<h4>Methods</h4>We performed chart review on 385 women and 193 men with UCPPS who enrolled in the MAPP-II SPS. 223 had cystoscopy and documentation of HL status. Among them, 12.5% had HL and 87.5% did not.<h4>Results</h4>UCPPS participants with HL were older, had increased nocturia, higher Interstitial Cystitis Symptom and Problem Indexes, and were more likely to report \"painful urgency\" compared with those without HL. On the other hand, UCPPS without HL reported more intense nonurologic pain, greater distribution of pain outside the pelvis, greater numbers of comorb"],"journal":["Neurourology and urodynamics"],"pubmed_title":["Comparison of deep phenotyping features of UCPPS with and without Hunner lesion: A MAPP-II Research Network Study."],"pmcid":["PMC8159180"],"funding_grant_id":["U24 DK082333","U01 DK082370","U01 DK103227","U24 DK082316","U01 DK082333","U01 DK082344","U01 DK082345","DK082315 (Andriole : G; Lai : H) : DK082316 (Landis)","U01 DK082342","U01 DK082315","U01 DK082316","U01 DK082325","U01 DK103260","U01 DK103271"],"pubmed_authors":["Newcomb C","Landis JR","Appleby D","Anger JT","MAPP Research Network","Nickel JC","Lai HH","Rodriguez LV","Harte S","Ackerman AL","Gupta P","Clemens JQ"],"additional_accession":[]},"is_claimable":false,"name":"Comparison of deep phenotyping features of UCPPS with and without Hunner lesion: A MAPP-II Research Network Study.","description":"<h4>Objective</h4>To use the phenotyping data from the MAPP-II Symptom Patterns Study (SPS) to compare the systemic features between urologic chronic pelvic pain syndrome (UCPPS) with Hunner lesion (HL) versus those without HL.<h4>Methods</h4>We performed chart review on 385 women and 193 men with UCPPS who enrolled in the MAPP-II SPS. 223 had cystoscopy and documentation of HL status. Among them, 12.5% had HL and 87.5% did not.<h4>Results</h4>UCPPS participants with HL were older, had increased nocturia, higher Interstitial Cystitis Symptom and Problem Indexes, and were more likely to report \"painful urgency\" compared with those without HL. On the other hand, UCPPS without HL reported more intense nonurologic pain, greater distribution of pain outside the pelvis, greater numbers of comorb","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Mar","modification":"2025-04-05T10:03:59.87Z","creation":"2025-04-05T10:03:59.87Z"},"accession":"S-EPMC8159180","cross_references":{"pubmed":["33604963"],"doi":["10.1002/nau.24623"]}}