biostudies-literatureKatz DINIA NIH HHSNINDS NIH HHSNIGMS NIH HHS848-863https://www.ebi.ac.uk/biostudies/studies/S-EPMC8166432biostudies-literatureUnknown96(18)<h4>Objective</h4>To develop evidence-informed, expert consensus research diagnostic criteria for traumatic encephalopathy syndrome (TES), the clinical disorder associated with neuropathologically diagnosed chronic traumatic encephalopathy (CTE).<h4>Methods</h4>A panel of 20 expert clinician-scientists in neurology, neuropsychology, psychiatry, neurosurgery, and physical medicine and rehabilitation, from 11 academic institutions, participated in a modified Delphi procedure to achieve consensus, initiated at the First National Institute of Neurological Disorders and Stroke Consensus Workshop to Define the Diagnostic Criteria for TES<i>,</i> April, 2019. Before consensus, panelists reviewed evidence from all published cases of CTE with neuropathologic confirmation, and they examined the predNeurologyNational Institute of Neurological Disorders and Stroke Consensus Diagnostic Criteria for Traumatic Encephalopathy Syndrome.PMC8166432P20 GM109025P20 AG068053P30 AG019610U01 NS093334U54 NS115322K23 NS102399R01 AG057708P30 AG072980Mez JJordan BDShenton MEPeskind ERKoroshetz WJDodick DWCummings JLMcKee ACAlosco MLMcAllister TWBanks SJBernick CReiman EMBrody DLAdler CHBabcock DJFoley EMStern RAPetersen RCBarr WBDams-O'Connor KGeda YEBalcer LJZafonte RDMariani MLCantu RCTripodis YWethe JVKatz DIfalseNational Institute of Neurological Disorders and Stroke Consensus Diagnostic Criteria for Traumatic Encephalopathy Syndrome.<h4>Objective</h4>To develop evidence-informed, expert consensus research diagnostic criteria for traumatic encephalopathy syndrome (TES), the clinical disorder associated with neuropathologically diagnosed chronic traumatic encephalopathy (CTE).<h4>Methods</h4>A panel of 20 expert clinician-scientists in neurology, neuropsychology, psychiatry, neurosurgery, and physical medicine and rehabilitation, from 11 academic institutions, participated in a modified Delphi procedure to achieve consensus, initiated at the First National Institute of Neurological Disorders and Stroke Consensus Workshop to Define the Diagnostic Criteria for TES<i>,</i> April, 2019. Before consensus, panelists reviewed evidence from all published cases of CTE with neuropathologic confirmation, and they examined the pred2021-01-01T00:00:00Z2021 May2025-05-18T12:06:08.154Z2025-04-05T20:40:48.752ZS-EPMC81664323372299010.1212/wnl.000000000001185010.1212/WNL.0000000000011850