{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Mantripragada VP"],"funding":["National Institutes of Health"],"pagination":["107129"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8170068"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["37"],"pubmed_abstract":["Osteoarthritis (OA) is a leading cause of disability in older adults and takes substantial toll at personal, economic and societal levels. There is inadequate comprehension of OA disease progression specifically during the early phases of OA. This knowledge is critical to understanding the heterogeneity in OA progression as well as enable development of targeted therapeutics at the start of the disease rather than end-stage. Histopathology of cartilage is a common method used to assess in situ state of cartilage tissue. The data presented in this article assesses the histopathological status of human cartilage specimens collected from 90 patients (<i>n</i> = 180). Each specimen was processed for histology and stained with hematoxylin and eosin (HE) and safranin O fast-green (SafO) for acqu"],"journal":["Data in brief"],"pubmed_title":["A comprehensive dataset of histopathology images, grades and patient demographics for human Osteoarthritis Cartilage."],"pmcid":["PMC8170068"],"funding_grant_id":["R01 AR063733"],"pubmed_authors":["Piuzzi NS","Muschler GF","Midura RJ","Erdemir A","Mantripragada VP"],"additional_accession":[]},"is_claimable":false,"name":"A comprehensive dataset of histopathology images, grades and patient demographics for human Osteoarthritis Cartilage.","description":"Osteoarthritis (OA) is a leading cause of disability in older adults and takes substantial toll at personal, economic and societal levels. There is inadequate comprehension of OA disease progression specifically during the early phases of OA. This knowledge is critical to understanding the heterogeneity in OA progression as well as enable development of targeted therapeutics at the start of the disease rather than end-stage. Histopathology of cartilage is a common method used to assess in situ state of cartilage tissue. The data presented in this article assesses the histopathological status of human cartilage specimens collected from 90 patients (<i>n</i> = 180). Each specimen was processed for histology and stained with hematoxylin and eosin (HE) and safranin O fast-green (SafO) for acqu","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Aug","modification":"2025-04-04T14:59:53.494Z","creation":"2022-02-10T14:35:16.407Z"},"accession":"S-EPMC8170068","cross_references":{"pubmed":["34113698"],"doi":["10.1016/j.dib.2021.107129"]}}