biostudies-literatureXu MPriority Academic Program Development of Jiangsu Higher Education InstitutionsNational Natural Science Foundation of ChinaWelch FoundationNatural Science Foundation of Jiangsu Province4104-4110https://www.ebi.ac.uk/biostudies/studies/S-EPMC8179526biostudies-literatureUnknown12(11)Modulating different stacking modes of nanoscale metal-organic frameworks (MOFs) introduces different properties and functionalities but remains a great challenge. Here, we describe a morphology engineering method to modulate the stacking modes of nanoscale NU-901. The nanoscale NU-901 is stacked through solvent removal after one-pot solvothermal synthesis, in which different morphologies from nanosheets (NS) to interpenetrated nanosheets (I-NS) and nanoparticles (NP) were obtained successfully. The stacked NU-901-NS, NU-901-I-NS, and NU-901-NP exhibited relatively aligned stacking, random stacking, and close packing, respectively. The three stacked nanoscale NU-901 exhibited different separation abilities and all showed better performance than bulk phase NU-901. Our work provides a new moChemical scienceModulating the stacking modes of nanosized metal-organic frameworks by morphology engineering for isomer separation.PMC8179526A-0030BK2019008621922407Xu MYin YDCai PMeng SSTang WQPowell JAZhou HCGu ZYfalseModulating the stacking modes of nanosized metal-organic frameworks by morphology engineering for isomer separation.Modulating different stacking modes of nanoscale metal-organic frameworks (MOFs) introduces different properties and functionalities but remains a great challenge. Here, we describe a morphology engineering method to modulate the stacking modes of nanoscale NU-901. The nanoscale NU-901 is stacked through solvent removal after one-pot solvothermal synthesis, in which different morphologies from nanosheets (NS) to interpenetrated nanosheets (I-NS) and nanoparticles (NP) were obtained successfully. The stacked NU-901-NS, NU-901-I-NS, and NU-901-NP exhibited relatively aligned stacking, random stacking, and close packing, respectively. The three stacked nanoscale NU-901 exhibited different separation abilities and all showed better performance than bulk phase NU-901. Our work provides a new mo2021-01-01T00:00:00Z2021 Feb2025-04-22T00:31:57.655Z2022-02-10T16:03:45.405ZS-EPMC81795263416368110.1039/d0sc06747d