{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["17(4)"],"submitter":["Jillella AP"],"pubmed_abstract":["<h4>Purpose</h4>Acute promyelocytic leukemia (APL) is a curable leukemia with > 90% survival in clinical trials. Population-based studies from Sweden and US SEER data have shown long-term survival rates of 62% and 65.7%, with the lower rate being from a higher percentage of early deaths.<h4>Methods</h4>In this prospective, multicenter trial, we developed a simplified algorithm that focused on prevention and early treatment of the three main causes of death: bleeding, differentiation syndrome, and infection. All patients with a diagnosis of APL were included. The initial 6 months were spent educating oncologists about early deaths in APL. At the time of suspicion of an APL, an expert was contacted. The algorithm was made available followed by discussion of the treatment plan. Communication "],"journal":["JCO oncology practice"],"pagination":["e497-e505"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8202058"],"repository":["biostudies-literature"],"pubmed_title":["Comanagement Strategy Between Academic Institutions and Community Practices to Reduce Induction Mortality in Acute Promyelocytic Leukemia."],"pmcid":["PMC8202058"],"pubmed_authors":["Winton EF","El Geneidy MM","McLemore ML","Kota VK","Bolds SL","Grunwald MR","Gaddh M","Jillella AP","Simon KS","Krishnamurthy SH","Tongol J","DeBragga S","Langston AA","Caprara CR","Pati A","Heffner LT","Karkhanis P","Bashey A","Stuart RK","Cortes J","Zhang C","Arellano ML","Gerber JM"],"additional_accession":[]},"is_claimable":false,"name":"Comanagement Strategy Between Academic Institutions and Community Practices to Reduce Induction Mortality in Acute Promyelocytic Leukemia.","description":"<h4>Purpose</h4>Acute promyelocytic leukemia (APL) is a curable leukemia with > 90% survival in clinical trials. Population-based studies from Sweden and US SEER data have shown long-term survival rates of 62% and 65.7%, with the lower rate being from a higher percentage of early deaths.<h4>Methods</h4>In this prospective, multicenter trial, we developed a simplified algorithm that focused on prevention and early treatment of the three main causes of death: bleeding, differentiation syndrome, and infection. All patients with a diagnosis of APL were included. The initial 6 months were spent educating oncologists about early deaths in APL. At the time of suspicion of an APL, an expert was contacted. The algorithm was made available followed by discussion of the treatment plan. Communication ","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Apr","modification":"2025-06-01T02:51:37.54Z","creation":"2025-06-01T02:51:37.54Z"},"accession":"S-EPMC8202058","cross_references":{"pubmed":["33125295"],"doi":["10.1200/OP.20.00395"]}}