biostudies-literatureUnknown9(6)Tsuge I<i>Edwardsiella tarda</i> is an anaerobe associated with freshwater and marine life. Necrotizing soft tissue infection caused by <i>E. tarda</i> is rare, but its mortality rate is extremely high (61.1%). We experienced a survival case of Fournier's gangrene with <i>E. tarda</i>. A key clinical feature for the diagnosis was gas production; however, there have been no previous reports of such a phenomenon in relation to <i>E. tarda</i>. A 64-year-old man was admitted with a 3-day history of a high fever. His medical history, which included paraplegia from the Th6 level down, made the focus of inflammation at the perineum difficult to notice. Whole-body CT revealed subcutaneous gas from the posterior scrotum around the entire circumference of the anus. During emergency surgery, an incision atPlastic and reconstructive surgery. Global opene3625https://www.ebi.ac.uk/biostudies/studies/S-EPMC8205190biostudies-literatureFournier's Gangrene with <i>Edwardsiella tarda:</i> A Gas Production Case by Bacterial Synergism with <i>Streptococcus anginosus</i>.PMC8205190Matsui MTakahashi TTsuge ISakamoto MKanno TKaisho JYamanaka HKatsube MMorimoto NfalseFournier's Gangrene with <i>Edwardsiella tarda:</i> A Gas Production Case by Bacterial Synergism with <i>Streptococcus anginosus</i>.<i>Edwardsiella tarda</i> is an anaerobe associated with freshwater and marine life. Necrotizing soft tissue infection caused by <i>E. tarda</i> is rare, but its mortality rate is extremely high (61.1%). We experienced a survival case of Fournier's gangrene with <i>E. tarda</i>. A key clinical feature for the diagnosis was gas production; however, there have been no previous reports of such a phenomenon in relation to <i>E. tarda</i>. A 64-year-old man was admitted with a 3-day history of a high fever. His medical history, which included paraplegia from the Th6 level down, made the focus of inflammation at the perineum difficult to notice. Whole-body CT revealed subcutaneous gas from the posterior scrotum around the entire circumference of the anus. During emergency surgery, an incision at2021-01-01T00:00:00Z2021 Jun2025-04-19T17:45:01.952Z2022-02-10T15:45:45.358ZS-EPMC82051903415042310.1097/GOX.0000000000003625