biostudies-literatureUnknown12Chi BBHeavy metal pollution is a global knotty problem and fungi hold promising potential for the remediation of wastewater containing heavy metals. Here, a new highly chromium-tolerance species, <i>Penicillium janthinellum</i> P1, is investigated. The genome of P1 was sequenced and assembled into 30 Mb genome size containing 10,955 predicted protein-coding genes with a GC content of 46.16% through an integrated method of Illumina short-read sequencing and single-molecule real-time Pacific Biosciences sequencing platforms. Through a phylogenetic analysis with model species of fungi, the evolutionary divergence time of <i>Penicillium janthinellum</i> P1 and <i>Penicillium oxalicum</i> 114-2 was estimated to be 74 MYA. 33 secondary metabolism gene clusters were identified via antiSMASH software, mFrontiers in microbiology663217https://www.ebi.ac.uk/biostudies/studies/S-EPMC8212970biostudies-literatureSequencing and Comparative Genomic Analysis of a Highly Metal-Tolerant <i>Penicillium janthinellum</i> P1 Provide Insights Into Its Metal Tolerance.PMC8212970Chi BBShan YLiu HYLu YNChen HYYin PCfalseSequencing and Comparative Genomic Analysis of a Highly Metal-Tolerant <i>Penicillium janthinellum</i> P1 Provide Insights Into Its Metal Tolerance.Heavy metal pollution is a global knotty problem and fungi hold promising potential for the remediation of wastewater containing heavy metals. Here, a new highly chromium-tolerance species, <i>Penicillium janthinellum</i> P1, is investigated. The genome of P1 was sequenced and assembled into 30 Mb genome size containing 10,955 predicted protein-coding genes with a GC content of 46.16% through an integrated method of Illumina short-read sequencing and single-molecule real-time Pacific Biosciences sequencing platforms. Through a phylogenetic analysis with model species of fungi, the evolutionary divergence time of <i>Penicillium janthinellum</i> P1 and <i>Penicillium oxalicum</i> 114-2 was estimated to be 74 MYA. 33 secondary metabolism gene clusters were identified via antiSMASH software, m2021-01-01T00:00:00Z20212025-04-04T07:24:09.282Z2022-02-10T15:43:27.593ZS-EPMC82129703414965010.3389/fmicb.2021.663217