biostudies-literatureHaller HRobert Bosch Stiftung724https://www.ebi.ac.uk/biostudies/studies/S-EPMC8220783biostudies-literatureUnknown21(1)<h4>Background</h4>Cancer registries usually assess data of conventional treatments and/or patient survival. Beyond that, little is known about the influence of other predictors of treatment response related to the use of complementary therapies (CM) and lifestyle factors affecting patients' quality and quantity of life.<h4>Methods</h4>INTREST is a prospective cohort study collecting register data at multiple German certified cancer centers, which provide individualized, integrative, in- and outpatient breast cancer care. Patient-reported outcomes and clinical cancer data of anticipated N = 715 women with pTNM stage I-III breast cancer are collected using standardized case report forms at the time of diagnosis, after completing neo-/adjuvant chemotherapy, after completing adjuvant therapy BMC cancerThe INTREST registry: protocol of a multicenter prospective cohort study of predictors of women's response to integrative breast cancer treatment.PMC8220783KKF-2016-3Voiß PSauer GAppelbaum SHaller HKummel SPaul ADobos GCramer HReinisch MOstermann TfalseThe INTREST registry: protocol of a multicenter prospective cohort study of predictors of women's response to integrative breast cancer treatment.<h4>Background</h4>Cancer registries usually assess data of conventional treatments and/or patient survival. Beyond that, little is known about the influence of other predictors of treatment response related to the use of complementary therapies (CM) and lifestyle factors affecting patients' quality and quantity of life.<h4>Methods</h4>INTREST is a prospective cohort study collecting register data at multiple German certified cancer centers, which provide individualized, integrative, in- and outpatient breast cancer care. Patient-reported outcomes and clinical cancer data of anticipated N = 715 women with pTNM stage I-III breast cancer are collected using standardized case report forms at the time of diagnosis, after completing neo-/adjuvant chemotherapy, after completing adjuvant therapy 2021-01-01T00:00:00Z2021 Jun2026-07-16T06:10:12.943Z2022-02-10T16:28:47.761ZS-EPMC82207833416233910.1186/s12885-021-08468-2