biostudies-literatureDharwadkar PNational Cancer InstituteNCI NIH HHS353-361.e3https://www.ebi.ac.uk/biostudies/studies/S-EPMC8222407biostudies-literatureUnknown20(2)<h4>Background & aims</h4>Up to 20% of younger patients (age <50 years) diagnosed with colorectal cancer (CRC) have germline mutations in cancer susceptibility genes. Germline genetic testing may guide clinical management and facilitate earlier intervention in affected relatives. Few studies have characterized differences in genetic testing by race/ethnicity.<h4>Methods</h4>We identified young adults (age 18-49 years) diagnosed with CRC between 2009 and 2017 in 2 health systems in Dallas, TX. We evaluated referral to genetic counseling, attendance at genetic counseling appointments, and receipt of germline genetic testing by race/ethnicity.<h4>Results</h4>Of 385 patients with young-onset CRC (median age at diagnosis 44.4 years), 176 (45.7%) were Hispanic, 98 (25.4%) non-Hispanic Black, andClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological AssociationRacial and Ethnic Disparities in Germline Genetic Testing of Patients With Young-Onset Colorectal Cancer.PMC8222407P30 CA142543Dharwadkar PBurstein EMauer CSingal AGPirzadeh-Miller SLahiri SGreenan GStoffel EMMurphy CCfalseRacial and Ethnic Disparities in Germline Genetic Testing of Patients With Young-Onset Colorectal Cancer.<h4>Background & aims</h4>Up to 20% of younger patients (age <50 years) diagnosed with colorectal cancer (CRC) have germline mutations in cancer susceptibility genes. Germline genetic testing may guide clinical management and facilitate earlier intervention in affected relatives. Few studies have characterized differences in genetic testing by race/ethnicity.<h4>Methods</h4>We identified young adults (age 18-49 years) diagnosed with CRC between 2009 and 2017 in 2 health systems in Dallas, TX. We evaluated referral to genetic counseling, attendance at genetic counseling appointments, and receipt of germline genetic testing by race/ethnicity.<h4>Results</h4>Of 385 patients with young-onset CRC (median age at diagnosis 44.4 years), 176 (45.7%) were Hispanic, 98 (25.4%) non-Hispanic Black, and2022-01-01T00:00:00Z2022 Feb2025-04-05T09:05:51.459Z2025-04-05T09:05:51.459ZS-EPMC82224073335972810.1016/j.cgh.2020.12.025