biostudies-literatureHsu BMThis research was funded by the Ministry of Science and Technology of Taiwan , the Buddhist Tzu Chi Hospital and Asia University Hospital. This research was also supported by Ditmanson Medical Foundation Chia - Yi Christian Hospital and the Center for Inn748https://www.ebi.ac.uk/biostudies/studies/S-EPMC8235027biostudies-literatureUnknown10(6)To provide evidence of the cross-contamination of emerging pathogenic microbes in a local network between long-term care facilities (LTCFs) and hospitals, this study emphasizes the molecular typing, the prevalence of virulence genes, and the antibiotic resistance pattern of methicillin-resistant <i>Staphylococcus aureus</i>. MRSA isolates were characterized from 246 samples collected from LTCFs, medical tubes of LTCF residents, and hospital environments of two cities, Chiayi and Changhua. Species identification, molecular characterization, and drug resistance analysis were performed. Hospital environments had a higher MRSA detection rate than that of LTCF environments, where moist samples are a hotspot of MRSA habitats, including tube samples from LTCF residents. All MRSA isolates in this Antibiotics (Basel, Switzerland)Molecular and Anti-Microbial Resistance (AMR) Profiling of Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA) from Hospital and Long-Term Care Facilities (LTCF) Environment.PMC8235027(MOST 108-2116-M-194 -005 & 108-2811-M-194 -507), (RCN011)Chen JSKoner SHussain BLin ICHsu BMHuang SWTsai HCHsu GJfalseMolecular and Anti-Microbial Resistance (AMR) Profiling of Methicillin-Resistant <i>Staphylococcus aureus</i> (MRSA) from Hospital and Long-Term Care Facilities (LTCF) Environment.To provide evidence of the cross-contamination of emerging pathogenic microbes in a local network between long-term care facilities (LTCFs) and hospitals, this study emphasizes the molecular typing, the prevalence of virulence genes, and the antibiotic resistance pattern of methicillin-resistant <i>Staphylococcus aureus</i>. MRSA isolates were characterized from 246 samples collected from LTCFs, medical tubes of LTCF residents, and hospital environments of two cities, Chiayi and Changhua. Species identification, molecular characterization, and drug resistance analysis were performed. Hospital environments had a higher MRSA detection rate than that of LTCF environments, where moist samples are a hotspot of MRSA habitats, including tube samples from LTCF residents. All MRSA isolates in this 2021-01-01T00:00:00Z2021 Jun2025-04-05T13:08:57.622Z2022-02-10T18:39:58.064ZS-EPMC82350273420555210.3390/antibiotics10060748