{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Hummel S"],"funding":["National Institute of Environmental Health Sciences","Eunice Kennedy Shriver National Institute of Child Health and Human Development","NCATS NIH HHS","National Institute of Diabetes and Digestive and Kidney Diseases","Juvenile Diabetes Research Foundation","NIH","German Federal Ministry of Education and Research","National Institute of Allergy and Infectious Diseases","National Center for Advancing Translational Sciences Clinical and Translational Science","German Center for Diabetes Research","University of Florida","NIDDK NIH HHS","NLM NIH HHS","University of Colorado"],"pagination":["134-142"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8246624"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["114(1)"],"pubmed_abstract":["<h4>Background</h4>Breastfeeding has beneficial effects on numerous health outcomes.<h4>Objectives</h4>We investigated whether breastfeeding duration is associated with the development of early childhood autoimmunity, allergies, or obesity in a multinational prospective birth cohort.<h4>Methods</h4>Infants with genetic susceptibility for type 1 diabetes (n = 8676) were followed for the development of autoantibodies to islet autoantigens or transglutaminase, allergies, and for anthropometric measurements to a median age of 8.3 y (IQR: 2.8-10.2 y). Information on breastfeeding was collected at 3 mo of age and prospectively thereafter. A propensity score for longer breastfeeding was calculated from the variables that were likely to influence any or exclusive breastfeeding. The risks of develo"],"journal":["The American journal of clinical nutrition"],"pubmed_title":["Associations of breastfeeding with childhood autoimmunity, allergies, and overweight: The Environmental Determinants of Diabetes in the Young (TEDDY) study."],"pmcid":["PMC8246624"],"funding_grant_id":["U01 DK63863","U01 DK63861","UC4 DK117483","UL1 TR002535","U01 DK063821","U01 DK063865","U01 DK63821","U01 DK63865","U01 DK063863","UC4 DK63821","UC4 DK63865","U01 DK63829","UC4 DK112243","UC4 DK63861","UC4 DK63863","UL1 TR000064","FKZ 01KX1818","UC4 DK95300","UC4 DK063821","U01 DK63790","UC4 DK063865","UC4 DK63829","U01 DK63836","UC4 DK100238","UC4 DK106955","FKZ 01EA1905","UC4 DK63836","HHSN267200700014C"],"pubmed_authors":["Lynch K","Uusitalo U","Hagopian WA","Aronsson CA","TEDDY Study Group","Rewers MJ","Virtanen SM","Lernmark A","Weiß A","Krischer JP","Beyerlein A","She JX","Ziegler AG","Agardh D","Akolkar B","Hummel S","Koletzko S","Vehik K","Bonifacio E","Toppari J","Norris JM"],"additional_accession":[]},"is_claimable":false,"name":"Associations of breastfeeding with childhood autoimmunity, allergies, and overweight: The Environmental Determinants of Diabetes in the Young (TEDDY) study.","description":"<h4>Background</h4>Breastfeeding has beneficial effects on numerous health outcomes.<h4>Objectives</h4>We investigated whether breastfeeding duration is associated with the development of early childhood autoimmunity, allergies, or obesity in a multinational prospective birth cohort.<h4>Methods</h4>Infants with genetic susceptibility for type 1 diabetes (n = 8676) were followed for the development of autoantibodies to islet autoantigens or transglutaminase, allergies, and for anthropometric measurements to a median age of 8.3 y (IQR: 2.8-10.2 y). Information on breastfeeding was collected at 3 mo of age and prospectively thereafter. A propensity score for longer breastfeeding was calculated from the variables that were likely to influence any or exclusive breastfeeding. The risks of develo","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Jul","modification":"2025-04-05T10:03:12.378Z","creation":"2025-04-05T10:03:12.378Z"},"accession":"S-EPMC8246624","cross_references":{"pubmed":["33831944"],"doi":["10.1093/ajcn/nqab065"]}}