biostudies-literatureUnknown9(2)Riar S<h4>Background</h4>In Canada, decisions regarding osteoporosis pharmacotherapy are based on estimated 10-year risk of osteoporotic fracture. We aimed to determine how frequently 2 common approaches (Canadian Association of Radiologists and Osteoporosis Canada [CAROC] tool and Fracture Risk Assessment Tool [FRAX]) produced different estimates and to seek possible explanations for differences.<h4>Methods</h4>We conducted a cross-sectional chart review at a tertiary osteoporosis centre (Dr. David Hanley Osteoporosis Centre in Calgary). Included patients were women referred for consideration of osteoporosis pharmacotherapy who attended a consultation between 2016 and 2019 and whose charts contained 10-year osteoporotic fracture risk estimates using both the CAROC tool (based on bone mineral deCMAJ openE711-E717https://www.ebi.ac.uk/biostudies/studies/S-EPMC8248580biostudies-literatureComparison of 2 fracture risk estimation processes in Alberta: a cross-sectional chart review.PMC8248580Frohlich DBillington EOFeasel ALSymonds CJAghajafari FRiar SKline GAfalseComparison of 2 fracture risk estimation processes in Alberta: a cross-sectional chart review.<h4>Background</h4>In Canada, decisions regarding osteoporosis pharmacotherapy are based on estimated 10-year risk of osteoporotic fracture. We aimed to determine how frequently 2 common approaches (Canadian Association of Radiologists and Osteoporosis Canada [CAROC] tool and Fracture Risk Assessment Tool [FRAX]) produced different estimates and to seek possible explanations for differences.<h4>Methods</h4>We conducted a cross-sectional chart review at a tertiary osteoporosis centre (Dr. David Hanley Osteoporosis Centre in Calgary). Included patients were women referred for consideration of osteoporosis pharmacotherapy who attended a consultation between 2016 and 2019 and whose charts contained 10-year osteoporotic fracture risk estimates using both the CAROC tool (based on bone mineral de2021-01-01T00:00:00Z2021 Apr-Jun2026-07-16T12:55:42.917Z2026-07-09T10:56:24.795ZS-EPMC82485803416266310.9778/cmajo.20200207