biostudies-literaturePohl HNCATS NIH HHSMedtronicAmerican College of GastroenterologyColonary SolutionsOlympusBoston ScientificColoWrapEndoChoiceNational Institutes of HealthCosmoUS EndoscopyErbeExact SciencesPentaxNIDDK NIH HHSFonds de Recherche du Québec SantéEndoAid119-128.e2https://www.ebi.ac.uk/biostudies/studies/S-EPMC8262363biostudies-literatureUnknown159(1)<h4>Background & aims</h4>There is debate over the type of electrosurgical setting that should be used for polyp resection. Some endoscopists use a type of blended current (yellow), whereas others prefer coagulation (blue). We performed a single-blinded, randomized trial to determine whether type of electrosurgical setting affects risk of adverse events or recurrence.<h4>Methods</h4>Patients undergoing endoscopic mucosal resection of nonpedunculated colorectal polyps 20 mm or larger (n = 928) were randomly assigned, in a 2 × 2 design, to groups that received clip closure or no clip closure of the resection defect (primary intervention) and then to either a blended current (Endocut Q) or coagulation current (forced coagulation) (Erbe Inc) (secondary intervention and focus of the study). TheGastroenterologyEffects of Blended (Yellow) vs Forced Coagulation (Blue) Currents on Adverse Events, Complete Resection, or Polyp Recurrence After Polypectomy in a Large Randomized Trial.PMC8262363KL2TR001109KL2 TR001109UL1 TR001863P30 DK123704Hasan MKPleskow Dvon Renteln DLevenick JMMathew ARastogi AAntaki FLaw RJElmunzer BJSanaei OMoyer MTCrockett SDGordon SRPellise MKhashab MARex DKGrimm ISAl-Kawas FHElias PAAslanian HRPohl HMackenzie TAGill JAfalseEffects of Blended (Yellow) vs Forced Coagulation (Blue) Currents on Adverse Events, Complete Resection, or Polyp Recurrence After Polypectomy in a Large Randomized Trial.<h4>Background & aims</h4>There is debate over the type of electrosurgical setting that should be used for polyp resection. Some endoscopists use a type of blended current (yellow), whereas others prefer coagulation (blue). We performed a single-blinded, randomized trial to determine whether type of electrosurgical setting affects risk of adverse events or recurrence.<h4>Methods</h4>Patients undergoing endoscopic mucosal resection of nonpedunculated colorectal polyps 20 mm or larger (n = 928) were randomly assigned, in a 2 × 2 design, to groups that received clip closure or no clip closure of the resection defect (primary intervention) and then to either a blended current (Endocut Q) or coagulation current (forced coagulation) (Erbe Inc) (secondary intervention and focus of the study). The2020-01-01T00:00:00Z2020 Jul2026-05-09T07:54:27.504Z2022-02-10T18:29:15.371ZS-EPMC82623633217347810.1053/j.gastro.2020.03.014