{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"omics_type":["Unknown"],"volume":["8"],"submitter":["Charmet T"],"pubmed_abstract":["<h4>Background</h4>We aimed to assess the effectiveness of two doses of mRNA COVID-19 vaccines against COVID-19 with the original virus and other lineages circulating in France.<h4>Methods</h4>In this nationwide case-control study, cases were SARS-CoV-2 infected adults with onset of symptoms between 14 February and 3 May 2021. Controls were non-infected adults from a national representative panel matched to cases by age, sex, region, population density and calendar week. Participants completed an online questionnaire on recent activity-related exposures and vaccination history. Information about the infecting virus was based on a screening RT-PCR for either B.1.1.7 or B.1.351/P.1 variants.<h4>Findings</h4>Included in our analysis were 7 288 adults infected with the original SARS-CoV-2 viru"],"journal":["The Lancet regional health. Europe"],"pagination":["100171"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8277121"],"repository":["biostudies-literature"],"pubmed_title":["Impact of original, B.1.1.7, and B.1.351/P.1 SARS-CoV-2 lineages on vaccine effectiveness of two doses of COVID-19 mRNA vaccines: Results from a nationwide case-control study in France."],"pmcid":["PMC8277121"],"pubmed_authors":["Septfons A","van der Werf S","Grant R","Maurizot A","Rogoff A","Galmiche S","Cheny O","Mailles A","Schaeffer L","Omar F","David C","Von Platen C","Charmet T","Gaymard A","Carrat F","Fontanet A","Cauchemez S","Enouf V","Levy-Bruhl D","Lina B","Lefrancois LH"],"additional_accession":[]},"is_claimable":false,"name":"Impact of original, B.1.1.7, and B.1.351/P.1 SARS-CoV-2 lineages on vaccine effectiveness of two doses of COVID-19 mRNA vaccines: Results from a nationwide case-control study in France.","description":"<h4>Background</h4>We aimed to assess the effectiveness of two doses of mRNA COVID-19 vaccines against COVID-19 with the original virus and other lineages circulating in France.<h4>Methods</h4>In this nationwide case-control study, cases were SARS-CoV-2 infected adults with onset of symptoms between 14 February and 3 May 2021. Controls were non-infected adults from a national representative panel matched to cases by age, sex, region, population density and calendar week. Participants completed an online questionnaire on recent activity-related exposures and vaccination history. Information about the infecting virus was based on a screening RT-PCR for either B.1.1.7 or B.1.351/P.1 variants.<h4>Findings</h4>Included in our analysis were 7 288 adults infected with the original SARS-CoV-2 viru","dates":{"release":"2021-01-01T00:00:00Z","publication":"2021 Sep","modification":"2026-05-07T22:59:00.372Z","creation":"2022-02-11T15:36:40.637Z"},"accession":"S-EPMC8277121","cross_references":{"pubmed":["34278372"],"doi":["10.1016/j.lanepe.2021.100171"]}}