{"database":"biostudies-literature","file_versions":[],"scores":null,"additional":{"submitter":["Albert C"],"funding":["Baskent Üniversitesi","NIDDK NIH HHS","Dr. Werner Jackstädt-Stiftung","Foundation for the National Institutes of Health","B. Braun-Stiftung"],"pagination":["826-841.e1"],"full_dataset_link":["https://www.ebi.ac.uk/biostudies/studies/S-EPMC8283708"],"repository":["biostudies-literature"],"omics_type":["Unknown"],"volume":["76(6)"],"pubmed_abstract":["<h4>Rationale & objective</h4>The usefulness of measures of neutrophil gelatinase-associated lipocalin (NGAL) in urine or plasma obtained on clinical laboratory platforms for predicting acute kidney injury (AKI) and AKI requiring dialysis (AKI-D) has not been fully evaluated. We sought to quantitatively summarize published data to evaluate the value of urinary and plasma NGAL for kidney risk prediction.<h4>Study design</h4>Literature-based meta-analysis and individual-study-data meta-analysis of diagnostic studies following PRISMA-IPD guidelines.<h4>Setting & study populations</h4>Studies of adults investigating AKI, severe AKI, and AKI-D in the setting of cardiac surgery, intensive care, or emergency department care using either urinary or plasma NGAL measured on clinical laboratory platf"],"journal":["American journal of kidney diseases : the official journal of the National Kidney Foundation"],"pubmed_title":["Neutrophil Gelatinase-Associated Lipocalin Measured on Clinical Laboratory Platforms for the Prediction of Acute Kidney Injury and the Associated Need for Dialysis Therapy: A Systematic Review and Meta-analysis."],"pmcid":["PMC8283708"],"funding_grant_id":["P50 DK096418"],"pubmed_authors":["Camou F","Zapf A","Kim H","Di Somma S","de Geus HRH","Nanas S","Cruz D","Devarajan P","Nickolas TL","Braun-Dullaeus RC","Kavalci C","Chen Z","Soto K","Lentini P","Pipili C","Endre ZH","Hjortrup PB","Rover C","Karaolanis G","Lipcsey M","Martensson J","Ralib A","Pickering JW","Ronco C","Chocron S","Rosa-Diez GJ","Liebetrau C","Haase M","Haase-Fielitz A","Bellomo R","Heinz J","Muller C","Doi K","Garcia-Alvarez M","Albert A","Breidthardt T","Albert C","Hur M"],"additional_accession":[]},"is_claimable":false,"name":"Neutrophil Gelatinase-Associated Lipocalin Measured on Clinical Laboratory Platforms for the Prediction of Acute Kidney Injury and the Associated Need for Dialysis Therapy: A Systematic Review and Meta-analysis.","description":"<h4>Rationale & objective</h4>The usefulness of measures of neutrophil gelatinase-associated lipocalin (NGAL) in urine or plasma obtained on clinical laboratory platforms for predicting acute kidney injury (AKI) and AKI requiring dialysis (AKI-D) has not been fully evaluated. We sought to quantitatively summarize published data to evaluate the value of urinary and plasma NGAL for kidney risk prediction.<h4>Study design</h4>Literature-based meta-analysis and individual-study-data meta-analysis of diagnostic studies following PRISMA-IPD guidelines.<h4>Setting & study populations</h4>Studies of adults investigating AKI, severe AKI, and AKI-D in the setting of cardiac surgery, intensive care, or emergency department care using either urinary or plasma NGAL measured on clinical laboratory platf","dates":{"release":"2020-01-01T00:00:00Z","publication":"2020 Dec","modification":"2025-05-29T21:28:21.466Z","creation":"2022-02-10T20:13:06.101Z"},"accession":"S-EPMC8283708","cross_references":{"pubmed":["32679151"],"doi":["10.1053/j.ajkd.2020.05.015"]}}